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פותח על ידי קלירמאש פתרונות בע"מ -
Cypermethrin synergism by pyrethroid esterase inhibitors in adults of the whitefly Bemisia tabaci
Year:
1987
Authors :
אשר, קורט רודולף
;
.
ישעיה, יצחק
;
.
מנדלסון, זמירה
;
.
Volume :
28
Co-Authors:
Ishaaya, I., Department of Entomology, ARO, The Volcani Center, Bet Dagan 50-250, Israel
Mendelson, Z., Department of Entomology, ARO, The Volcani Center, Bet Dagan 50-250, Israel
Ascher, K.R.S., Department of Toxicology, ARO, The Volcani Center, Bet Dagan 50-250, Israel
Casida, J.E., Pesticide Chemistry and Toxicology Laboratory, Department of Entomological Sciences, University of California, Berkeley, CA 94720, United States
Facilitators :
From page:
155
To page:
162
(
Total pages:
8
)
Abstract:
Pyrethroid esterases are a major factor in the tolerance of adults of the whitefly Bemesia tabaci to cypermethrin and related pyrethroids. This conclusion is based on the substrate specificity of these esterases and their inhibition by organophosphorus compounds acting as synergists. Whitefly esterases hydrolyze trans-permethrin faster than its cis-isomer or its α-cyano analogs trans- and cis-cypermethrin and deltamethrin. With trans-permethrin as the substrate, these pyrethroid esterases are sensitive to in vitro inhibition by monocrotophos and methamidophos (the active metabolite of acephate) with 50% inhibition at 9 × 10-7 and 10-5 M, respectively. The potency of cypermethrin under glasshouse conditions is synergized 5- to 50-fold by monocrotophos, acephate or methidathion and it is also greatly increased by profenofos, with synergist:pyrethroid ratios ranging from 1:8 to 8:1. Cypermethrin toxicity under field conditions in cotton is strongly synergized and the effective period for whitefly control is prolonged by adding an equal weight of monocrotophos or acephate or 8 parts of methidation to 1 part pyrethroid. Mouse liver pyrethroid esterases hydrolyzing cis-cypermethrin are inhibited by low intraperitoneal doses of profenofos and acephate but not monocrotophos and methidathion. The high magnitude of cypermethrin synergism in whiteflies is not repeated in mice, perhaps due to differences in the toxicological importance and inhibitor specificities of esterases involved in detoxification. © 1987.
Note:
Related Files :
acephate
animal cell
animal experiment
intoxication
liver
methamidophos
profenofos
therapy
unclassified drug
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/0048-3575(87)90014-9
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
18404
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:21
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Scientific Publication
Cypermethrin synergism by pyrethroid esterase inhibitors in adults of the whitefly Bemisia tabaci
28
Ishaaya, I., Department of Entomology, ARO, The Volcani Center, Bet Dagan 50-250, Israel
Mendelson, Z., Department of Entomology, ARO, The Volcani Center, Bet Dagan 50-250, Israel
Ascher, K.R.S., Department of Toxicology, ARO, The Volcani Center, Bet Dagan 50-250, Israel
Casida, J.E., Pesticide Chemistry and Toxicology Laboratory, Department of Entomological Sciences, University of California, Berkeley, CA 94720, United States
Cypermethrin synergism by pyrethroid esterase inhibitors in adults of the whitefly Bemisia tabaci
Pyrethroid esterases are a major factor in the tolerance of adults of the whitefly Bemesia tabaci to cypermethrin and related pyrethroids. This conclusion is based on the substrate specificity of these esterases and their inhibition by organophosphorus compounds acting as synergists. Whitefly esterases hydrolyze trans-permethrin faster than its cis-isomer or its α-cyano analogs trans- and cis-cypermethrin and deltamethrin. With trans-permethrin as the substrate, these pyrethroid esterases are sensitive to in vitro inhibition by monocrotophos and methamidophos (the active metabolite of acephate) with 50% inhibition at 9 × 10-7 and 10-5 M, respectively. The potency of cypermethrin under glasshouse conditions is synergized 5- to 50-fold by monocrotophos, acephate or methidathion and it is also greatly increased by profenofos, with synergist:pyrethroid ratios ranging from 1:8 to 8:1. Cypermethrin toxicity under field conditions in cotton is strongly synergized and the effective period for whitefly control is prolonged by adding an equal weight of monocrotophos or acephate or 8 parts of methidation to 1 part pyrethroid. Mouse liver pyrethroid esterases hydrolyzing cis-cypermethrin are inhibited by low intraperitoneal doses of profenofos and acephate but not monocrotophos and methidathion. The high magnitude of cypermethrin synergism in whiteflies is not repeated in mice, perhaps due to differences in the toxicological importance and inhibitor specificities of esterases involved in detoxification. © 1987.
Scientific Publication
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