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אסיף מאגר המחקר החקלאי
פותח על ידי קלירמאש פתרונות בע"מ -
Relationships among age, eggshell thickness and vitamin D metabolism and its expression in the laying hen
Year:
1999
Authors :
בר, אריה
;
.
וקס, אליהו
;
.
Volume :
123
Co-Authors:
Bar, A., Institute of Animal Science, Agric. Res. Org., Volcani Ctr., P.O., Bet Dagan, Israel
Vax, E., Institute of Animal Science, Agric. Res. Org., Volcani Ctr., P.O., Bet Dagan, Israel
Striem, S., Institute of Animal Science, Agric. Res. Org., Volcani Ctr., P.O., Bet Dagan, Israel
Facilitators :
From page:
147
To page:
154
(
Total pages:
8
)
Abstract:
Hens forming uncalcified shells synthesized less 1,25- hydroxycholecalciferol (1,25(OH)2D3) and less duodenal and eggshell gland (ESG) calbindin than normal laying hens. Hens forming thin shells had lower intestinal and ESG calbindin and its mRNA. Reducing ESG calcium (Ca2+) transport by the carbonic anhydrase inhibitor acetazolamide, but not by dietary Ca2+ restriction, reduced ESG calbindin and its mRNA. Two sub- populations of hens characterized by shell thickness (ST) maintained this characteristic throughout the whole production period. The differences between the two sub-populations increased with age. In old laying hens, the two sub-populations responded differently to dietary Ca2+ restriction and to exogenous 1,25(OH)2D3. Those forming a thin shell responded to 1,25(OH)2D3 by a significant improvement in ST. The results suggest that: (a) the mechanism responsible for Ca2+ transport to the egg shell consists of a vitamin D-dependent absorption of Ca2+ and a multi-factor-dependent transfer of Ca2+ to the shell; (b) both steps are, most likely, calbindin- mediated; however, the induction of calbindin gene expression in the ESG is predominantly calcium-dependent; and (c) the apparent defect in vitamin D metabolism or its expression in old hens is typical of, or even exclusive, to thin-shell-forming hens.
Note:
Related Files :
aging
animal experiment
animal model
Animals
Egg Shell
Female
gene expression
Laying hen
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/S1095-6433(99)00039-2
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
19137
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:26
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Scientific Publication
Relationships among age, eggshell thickness and vitamin D metabolism and its expression in the laying hen
123
Bar, A., Institute of Animal Science, Agric. Res. Org., Volcani Ctr., P.O., Bet Dagan, Israel
Vax, E., Institute of Animal Science, Agric. Res. Org., Volcani Ctr., P.O., Bet Dagan, Israel
Striem, S., Institute of Animal Science, Agric. Res. Org., Volcani Ctr., P.O., Bet Dagan, Israel
Relationships among age, eggshell thickness and vitamin D metabolism and its expression in the laying hen
Hens forming uncalcified shells synthesized less 1,25- hydroxycholecalciferol (1,25(OH)2D3) and less duodenal and eggshell gland (ESG) calbindin than normal laying hens. Hens forming thin shells had lower intestinal and ESG calbindin and its mRNA. Reducing ESG calcium (Ca2+) transport by the carbonic anhydrase inhibitor acetazolamide, but not by dietary Ca2+ restriction, reduced ESG calbindin and its mRNA. Two sub- populations of hens characterized by shell thickness (ST) maintained this characteristic throughout the whole production period. The differences between the two sub-populations increased with age. In old laying hens, the two sub-populations responded differently to dietary Ca2+ restriction and to exogenous 1,25(OH)2D3. Those forming a thin shell responded to 1,25(OH)2D3 by a significant improvement in ST. The results suggest that: (a) the mechanism responsible for Ca2+ transport to the egg shell consists of a vitamin D-dependent absorption of Ca2+ and a multi-factor-dependent transfer of Ca2+ to the shell; (b) both steps are, most likely, calbindin- mediated; however, the induction of calbindin gene expression in the ESG is predominantly calcium-dependent; and (c) the apparent defect in vitamin D metabolism or its expression in old hens is typical of, or even exclusive, to thin-shell-forming hens.
Scientific Publication
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