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פותח על ידי קלירמאש פתרונות בע"מ -
DNA degradation and reduced recombination following UV irradiation during meiosis in yeast (Saccharomyces cerevisiae)
Year:
1976
Source of publication :
MGG Molecular & General Genetics
Authors :
זלץ, יחיעם
;
.
Volume :
146
Co-Authors:
Salts, Y., Department of Biology, University of California, San Diego, La Jolla, 92093, California, United States
Simchen, G., Department of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel
Piñon, R., Department of Biology, University of California, San Diego, La Jolla, 92093, California, United States
Facilitators :
From page:
55
To page:
59
(
Total pages:
5
)
Abstract:
Irradiation of meiotic yeast cells with moderate doses of ultraviolet irradiation (1,600 erg/mm2) leads to the arrest of premeiotic DNA synthesis, massive (5-40%) DNA degradation, and a 40-50% loss of cell viability. In contrast, such doses of UV irradiation had a minor effect on viability (15-20% loss) of logarithmically growing cells, and no comparable DNA degradation was observed in irradiated synchronized vegetative cells. Meiotic recombination is also affected by UV irradiation. When administered at a stage comparable to meiotic prophase, low doses of irradiation result in a reduction in recombination frequency without significantly affecting cell viability. © 1976 Springer-Verlag.
Note:
Related Files :
DNA
genetic recombination
genotype
microorganism
radioisotope
ultraviolet radiation
Ultraviolet Rays
uracil c 14
עוד תגיות
תוכן קשור
More details
DOI :
10.1007/BF00267983
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
19346
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:28
Scientific Publication
DNA degradation and reduced recombination following UV irradiation during meiosis in yeast (Saccharomyces cerevisiae)
146
Salts, Y., Department of Biology, University of California, San Diego, La Jolla, 92093, California, United States
Simchen, G., Department of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel
Piñon, R., Department of Biology, University of California, San Diego, La Jolla, 92093, California, United States
DNA degradation and reduced recombination following UV irradiation during meiosis in yeast (Saccharomyces cerevisiae)
Irradiation of meiotic yeast cells with moderate doses of ultraviolet irradiation (1,600 erg/mm2) leads to the arrest of premeiotic DNA synthesis, massive (5-40%) DNA degradation, and a 40-50% loss of cell viability. In contrast, such doses of UV irradiation had a minor effect on viability (15-20% loss) of logarithmically growing cells, and no comparable DNA degradation was observed in irradiated synchronized vegetative cells. Meiotic recombination is also affected by UV irradiation. When administered at a stage comparable to meiotic prophase, low doses of irradiation result in a reduction in recombination frequency without significantly affecting cell viability. © 1976 Springer-Verlag.
Scientific Publication
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