The sites of the spermicidal action of ethylene dibromide in bulls
Co-Authors:
Amir, D., Div. Anim. Reprod., Agric. Res. Organ., Volcani Cent., Bet Dagan, Israel
Abstract:
Sperm smears prepared from different parts of the genital tract of two bulls 12 and 21 days after the start of oral treatment with ethylene dibromide (4 mg EDB/kg body weight on alternate days), showed a distribution of abnormal spermatozoa, which indicates that EDB affected the shape of the spermatozoa during maturation in the epididymis and during spermiogenesis. After administration to four bulls of labeled [3H] or [14C]EDB, either orally or by injection, labeled spermatozoa were obtained in ejaculates collected from about 1 week after the first oral dose or injection until 2 to 3 weeks after the last oral dose or injection. The highest percentage of abnormal spermatozoa resulting from the treatment was found when the radioactivity of the spermatozoa was lowest or nil. It appears that the spermicidal action of EDB is not direct on the sperm cells but occurs during the process of spermiogenesis and through the absorptive and/or secretory functions of the epididymis.
Injections, Intraperitoneal
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Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:34
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