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Drug-Nutrient Interactions
Hasdai, A., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States
Liener, I.E., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States
Syrian golden hamsters fed diets of raw or heated soy flour for 16 months had an incidence (4%) of pancreatic neoplasms in both groups. Animals injected with N-nitrosobis (2-oxopropyl) amine (BOP) and fed heated soy flour for 15 months developed a high incidence (88%) of microscopic benign and malignant neoplasms, primarily of ductal origin. This was in marked contrast to a similar group of BOP-induced animals which had been fed raw soy flour and in which the incidence of pancreatic neoplasms was less than 10%.
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The effects of soy flour and N-nitrosobis (2-oxopropyl) amine on the pancreas of the hamster
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Hasdai, A., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States
Liener, I.E., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States
The effects of soy flour and N-nitrosobis (2-oxopropyl) amine on the pancreas of the hamster
Syrian golden hamsters fed diets of raw or heated soy flour for 16 months had an incidence (4%) of pancreatic neoplasms in both groups. Animals injected with N-nitrosobis (2-oxopropyl) amine (BOP) and fed heated soy flour for 15 months developed a high incidence (88%) of microscopic benign and malignant neoplasms, primarily of ductal origin. This was in marked contrast to a similar group of BOP-induced animals which had been fed raw soy flour and in which the incidence of pancreatic neoplasms was less than 10%.
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