אסיף מאגר המחקר החקלאי

The effects of soy flour and N-nitrosobis (2-oxopropyl) amine on the pancreas of the hamster

Year:

1985

Source of publication :

Authors :

Volume :

3

Co-Authors:

Hasdai, A., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States
Liener, I.E., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States

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Abstract:

Syrian golden hamsters fed diets of raw or heated soy flour for 16 months had an incidence (4%) of pancreatic neoplasms in both groups. Animals injected with N-nitrosobis (2-oxopropyl) amine (BOP) and fed heated soy flour for 15 months developed a high incidence (88%) of microscopic benign and malignant neoplasms, primarily of ductal origin. This was in marked contrast to a similar group of BOP-induced animals which had been fed raw soy flour and in which the incidence of pancreatic neoplasms was less than 10%.

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