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פותח על ידי קלירמאש פתרונות בע"מ -
Genetic mapping of quantitative trait loci for traits with ordinal distributions
Year:
1995
Source of publication :
Biometrics
Authors :
ולר, יהודה
;
.
Volume :
51
Co-Authors:
Hackett, C.A., Biomathematics/Statistics Scotland, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, United Kingdom
Weller, J.I., Biomathematics/Statistics Scotland, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, United Kingdom
Facilitators :
From page:
1252
To page:
1263
(
Total pages:
12
)
Abstract:
Statistical methods for mapping quantitative trait loci relative to genetic markers are now well established for continuous traits with normal distributions. However, many traits of economic importance are recorded on a discrete, ordinal scale. Here we describe a model developed for the analysis of ordinal traits, such its degree of difficulty in calving or categories of plant disease resistance. The model estimates the distance from the quantitative trait locus to neighbouring genetic markers, and also genetic parameters, either as gone effects on an underlying continuous scale or as probabilities of the observed categories. The model is tested on simulated data and is compared with an analysis based on mixtures of normal distributions. The ordinal model is found to estimate the parameters more accurately, especially when the number of categories is small or when only one linked marker is available.
Note:
Related Files :
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More details
DOI :
10.2307/2533257
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
20454
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:36
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Scientific Publication
Genetic mapping of quantitative trait loci for traits with ordinal distributions
51
Hackett, C.A., Biomathematics/Statistics Scotland, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, United Kingdom
Weller, J.I., Biomathematics/Statistics Scotland, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, United Kingdom
Genetic mapping of quantitative trait loci for traits with ordinal distributions
Statistical methods for mapping quantitative trait loci relative to genetic markers are now well established for continuous traits with normal distributions. However, many traits of economic importance are recorded on a discrete, ordinal scale. Here we describe a model developed for the analysis of ordinal traits, such its degree of difficulty in calving or categories of plant disease resistance. The model estimates the distance from the quantitative trait locus to neighbouring genetic markers, and also genetic parameters, either as gone effects on an underlying continuous scale or as probabilities of the observed categories. The model is tested on simulated data and is compared with an analysis based on mixtures of normal distributions. The ordinal model is found to estimate the parameters more accurately, especially when the number of categories is small or when only one linked marker is available.
Scientific Publication
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