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The Xanthomonas Ax21 protein is processed by the general secretory system and is secreted in association with outer membrane vesicles
Year:
2014
Source of publication :
PeerJ
Authors :
בהר, אופיר
;
.
Volume :
2013
Co-Authors:
Bahar, O., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Pruitt, R., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Luu, D.D., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Schwessinger, B., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Daudi, A., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Liu, F., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Ruan, R., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Fontaine-Bodin, L., UMR 186 IRD-Cirad, Université Montpellier 2 Résistance des Plantes aux Bioaggresseurs, Montpellier, France
Koebnik, R., UMR 186 IRD-Cirad, Université Montpellier 2 Résistance des Plantes aux Bioaggresseurs, Montpellier, France
Ronald, P., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States, UMR 186 IRD-Cirad, Université Montpellier 2 Résistance des Plantes aux Bioaggresseurs, Montpellier, France
Facilitators :
From page:
To page:
(
Total pages:
1
)
Abstract:
Pattern recognition receptors (PRRs) play an important role in detecting invading pathogens and mounting a robust defense response to restrict infection. In rice, one of the best characterized PRRs is XA21, a leucine rich repeat receptor-like kinase that confers broad-spectrum resistance to multiple strains of the bacterial pathogen Xanthomonas oryzae pv. oryzae (Xoo). In 2009 we reported that an Xoo protein, called Ax21, is secreted by a type I-secretion system and that it serves to activate XA21-mediated immunity. This report has recently been retracted. Here we present data that corrects our previous model.We first show that Ax21 secretion does not depend on the predicted type I secretion systemand that it is processed by the general secretion (Sec) system. We further show that Ax21 is an outer membrane protein, secreted in association with outer membrane vesicles. Finally, we provide data showing that ax21 knockout strains do not overcome XA21-mediated immunity. © 2014 Bahar et al.
Note:
Related Files :
immunity
Outer membrane vesicles
PAMPs
Plasmid
secretion
type I secretion system
unclassified drug
עוד תגיות
תוכן קשור
More details
DOI :
10.7717/peerj.242
Article number:
242
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
20515
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:37
Scientific Publication
The Xanthomonas Ax21 protein is processed by the general secretory system and is secreted in association with outer membrane vesicles
2013
Bahar, O., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Pruitt, R., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Luu, D.D., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Schwessinger, B., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Daudi, A., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Liu, F., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Ruan, R., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States
Fontaine-Bodin, L., UMR 186 IRD-Cirad, Université Montpellier 2 Résistance des Plantes aux Bioaggresseurs, Montpellier, France
Koebnik, R., UMR 186 IRD-Cirad, Université Montpellier 2 Résistance des Plantes aux Bioaggresseurs, Montpellier, France
Ronald, P., Department of Plant Pathology and the Genome Center, University of California, Davis, CA, United States, UMR 186 IRD-Cirad, Université Montpellier 2 Résistance des Plantes aux Bioaggresseurs, Montpellier, France
The Xanthomonas Ax21 protein is processed by the general secretory system and is secreted in association with outer membrane vesicles
Pattern recognition receptors (PRRs) play an important role in detecting invading pathogens and mounting a robust defense response to restrict infection. In rice, one of the best characterized PRRs is XA21, a leucine rich repeat receptor-like kinase that confers broad-spectrum resistance to multiple strains of the bacterial pathogen Xanthomonas oryzae pv. oryzae (Xoo). In 2009 we reported that an Xoo protein, called Ax21, is secreted by a type I-secretion system and that it serves to activate XA21-mediated immunity. This report has recently been retracted. Here we present data that corrects our previous model.We first show that Ax21 secretion does not depend on the predicted type I secretion systemand that it is processed by the general secretion (Sec) system. We further show that Ax21 is an outer membrane protein, secreted in association with outer membrane vesicles. Finally, we provide data showing that ax21 knockout strains do not overcome XA21-mediated immunity. © 2014 Bahar et al.
Scientific Publication
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