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אסיף מאגר המחקר החקלאי
פותח על ידי קלירמאש פתרונות בע"מ -
Multidrug-resistant Acinetobacter baumannii
Year:
2005
Source of publication :
Emerging Infectious Diseases
Authors :
המר-מונץ, אורלי
;
.
Volume :
11
Co-Authors:
Abbo, A., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Navon-Venezia, S., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Hammer-Muntz, O., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Krichali, T., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Siegman-Igra, Y., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Carmeli, Y., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, Division of Epidemiology, Tel Aviv Sourasky Medical Center, 6 Weizmann St, Tel Aviv 64239, Israel
Facilitators :
From page:
22
To page:
29
(
Total pages:
8
)
Abstract:
To understand the epidemiology of multidrug-resistant (MDR) Acinetobacter baumannii and define individual risk factors for multidrug resistance, we used epidemiologic methods, performed organism typing by pulsed-field gel electrophoresis (PFGE), and conducted a matched case-control retrospective study. We investigated 118 patients, on 27 wards in Israel, in whom MDR A. baumannii was isolated from clinical cultures. Each case-patient had a control without MDR A. baumannii and was matched for hospital length of stay, ward, and calendar time. The epidemiologic investigation found small clusters of up to 6 patients each with no common identified source. Ten different PFGE clones were found, of which 2 dominated. The PFGE pattern differed within temporospatial clusters, and antimicrobial drug susceptibility patterns varied within and between clones. Multivariate analysis identified the following significant risk factors: male sex, cardiovascular disease, having undergone mechanical ventilation, and having been treated with antimicrobial drugs (particularly metronidazole). Penicillins were protective. The complex epidemiology may explain why the emergence of MDR A. baumannii is difficult to control.
Note:
Related Files :
Acinetobacter baumannii
amikacin
Female
Israel
Male
risk factor
vancomycin
עוד תגיות
תוכן קשור
More details
DOI :
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
20689
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:38
Scientific Publication
Multidrug-resistant Acinetobacter baumannii
11
Abbo, A., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Navon-Venezia, S., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Hammer-Muntz, O., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Krichali, T., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Siegman-Igra, Y., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Carmeli, Y., Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, Division of Epidemiology, Tel Aviv Sourasky Medical Center, 6 Weizmann St, Tel Aviv 64239, Israel
Multidrug-resistant Acinetobacter baumannii
To understand the epidemiology of multidrug-resistant (MDR) Acinetobacter baumannii and define individual risk factors for multidrug resistance, we used epidemiologic methods, performed organism typing by pulsed-field gel electrophoresis (PFGE), and conducted a matched case-control retrospective study. We investigated 118 patients, on 27 wards in Israel, in whom MDR A. baumannii was isolated from clinical cultures. Each case-patient had a control without MDR A. baumannii and was matched for hospital length of stay, ward, and calendar time. The epidemiologic investigation found small clusters of up to 6 patients each with no common identified source. Ten different PFGE clones were found, of which 2 dominated. The PFGE pattern differed within temporospatial clusters, and antimicrobial drug susceptibility patterns varied within and between clones. Multivariate analysis identified the following significant risk factors: male sex, cardiovascular disease, having undergone mechanical ventilation, and having been treated with antimicrobial drugs (particularly metronidazole). Penicillins were protective. The complex epidemiology may explain why the emergence of MDR A. baumannii is difficult to control.
Scientific Publication
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