Folman, Y., Division of Physiology and Biochemistry of Reproduction, Department of Physiology, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States, Division of Physiology and Biochemistry of Reproduction, Department of Anatomy, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States, The Volcani Institute of Agricultural Research, Bet-Dagan, Israel
Ahmad, N., Division of Physiology and Biochemistry of Reproduction, Department of Physiology, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States, Division of Physiology and Biochemistry of Reproduction, Department of Anatomy, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States
Sowell, J.G., Division of Physiology and Biochemistry of Reproduction, Department of Physiology, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States, Division of Physiology and Biochemistry of Reproduction, Department of Anatomy, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States
Eik-Nes, K.B., Division of Physiology and Biochemistry of Reproduction, Department of Physiology, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States, Division of Physiology and Biochemistry of Reproduction, Department of Anatomy, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States
Ahmad, N., Division of Physiology and Biochemistry of Reproduction, Department of Physiology, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States, Division of Physiology and Biochemistry of Reproduction, Department of Anatomy, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States
Sowell, J.G., Division of Physiology and Biochemistry of Reproduction, Department of Physiology, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States, Division of Physiology and Biochemistry of Reproduction, Department of Anatomy, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States
Eik-Nes, K.B., Division of Physiology and Biochemistry of Reproduction, Department of Physiology, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States, Division of Physiology and Biochemistry of Reproduction, Department of Anatomy, University of Southern California, School of Medicine, Los Angeles, CA, 90033, United States
Testes of 13 immature and mature rats were separated into seminiferous tubules and interstitial tissue and incubated with 3H-testosterone (T) and an NADPH generating system. The per unit tissue wt conversion to 3H-5α-dihydrotestosterone (DHT) by incubated tubules from mature rats was much higher than that by incubated interstitial tissue. Both tissue components left more than 85% of the 3H-T substrate unconverted and total α-reduction of 3H-T was similar in both tubules and interstitial tissue. Interstitial tissue from testes of immature rats, however, converted more 3H-T to 3H-DHT than the testicular tubules and total 5α-reduction of T by the Leydig cells was 20 times greater than that of the tubules. © 1973 by The Endocrine Society.
