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פותח על ידי קלירמאש פתרונות בע"מ -
Effect of RH-5992 on adult development in the spruce budworm, Choristoneura fumiferana
Year:
2002
Authors :
ישעיה, יצחק
;
.
Volume :
32
Co-Authors:
Sundaram, M., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada, Department of Microbiology, University of Guelph, Guelph, Ont. N1G 2W1, Canada
Palli, S.R., Rohm and Haas Research Laboratories, 727 Norristown Road, Spring House, PA 19477, United States
Smagghe, G., Laboratory of Agrozoology, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium
Ishaaya, I., Department of Entomology, Agricultural Research Organization, Volcani Center, Bet Dagan 50250, Israel
Feng, Q.-L., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada
Primavera, M., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada
Tomkins, W.L., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada
Krell, P.J., Department of Microbiology, University of Guelph, Guelph, Ont. N1G 2W1, Canada
Retnakaran, A., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada
Facilitators :
From page:
225
To page:
231
(
Total pages:
7
)
Abstract:
The effect of RH-5992 (tebufenozide), a non-steroidal ecdysone agonist, on adult development of the spruce budworm, Choristoneura fumiferana, was investigated by administering the compound intrahemocoelically to pupae on days 1-6 after pupal ecdysis. At concentrations of 200 ng/pupa there was significant mortality but at doses of 50-100 ng/pupa, the emerging adults displayed wing deformities which reduced their ability to mate and oviposit. Light microscopy of the pupal wings revealed that there was degeneration of the epithelial cells, reduction in the number of veins, precocious cuticle formation and inhibition of growth of normal wing scales. Injection of RH-5992 into pupae resulted in a dose dependent induction of mRNA for ecdysone-induced transcription factor, Choristoneura hormone receptor 3 (CHR3). These results suggest that the pupae respond to RH-5992 in a manner similar to larvae. However, the effects are not expressed overtly and are camouflaged by the pharmacological effects. © 2002 Elsevier Science Ltd. All rights reserved.
Note:
Related Files :
Animal
animal tissue
biosynthesis
Conference paper
Genetics
Receptor
Reproduction
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/S0965-1748(01)00111-4
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר מתוך כינוס
;
.
Language:
אנגלית
Editors' remarks:
ID:
22044
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:48
You may also be interested in
Scientific Publication
Effect of RH-5992 on adult development in the spruce budworm, Choristoneura fumiferana
32
Sundaram, M., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada, Department of Microbiology, University of Guelph, Guelph, Ont. N1G 2W1, Canada
Palli, S.R., Rohm and Haas Research Laboratories, 727 Norristown Road, Spring House, PA 19477, United States
Smagghe, G., Laboratory of Agrozoology, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium
Ishaaya, I., Department of Entomology, Agricultural Research Organization, Volcani Center, Bet Dagan 50250, Israel
Feng, Q.-L., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada
Primavera, M., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada
Tomkins, W.L., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada
Krell, P.J., Department of Microbiology, University of Guelph, Guelph, Ont. N1G 2W1, Canada
Retnakaran, A., Great Lakes Forestry Center, Canadian Forest Service, Natural Resources Canada, 1219 Queen St. E., Sault Ste. Marie, Ont. P6A 5E5, Canada
Effect of RH-5992 on adult development in the spruce budworm, Choristoneura fumiferana
The effect of RH-5992 (tebufenozide), a non-steroidal ecdysone agonist, on adult development of the spruce budworm, Choristoneura fumiferana, was investigated by administering the compound intrahemocoelically to pupae on days 1-6 after pupal ecdysis. At concentrations of 200 ng/pupa there was significant mortality but at doses of 50-100 ng/pupa, the emerging adults displayed wing deformities which reduced their ability to mate and oviposit. Light microscopy of the pupal wings revealed that there was degeneration of the epithelial cells, reduction in the number of veins, precocious cuticle formation and inhibition of growth of normal wing scales. Injection of RH-5992 into pupae resulted in a dose dependent induction of mRNA for ecdysone-induced transcription factor, Choristoneura hormone receptor 3 (CHR3). These results suggest that the pupae respond to RH-5992 in a manner similar to larvae. However, the effects are not expressed overtly and are camouflaged by the pharmacological effects. © 2002 Elsevier Science Ltd. All rights reserved.
Scientific Publication
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