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פותח על ידי קלירמאש פתרונות בע"מ -
Juvenile hormone and juvenile hormone mimics inhibit proliferation in a lepidopteran imaginal disc cell line
Year:
2000
Source of publication :
Journal of Insect Physiology
Authors :
שעיה, אלי
;
.
Volume :
46
Co-Authors:
Oberlander, H., Center for Medical, Agric. Vet. Entomol., Agric. Res. S., Gainesville, FL 32604, United States
Leach, C.E., Center for Medical, Agric. Vet. Entomol., Agric. Res. S., Gainesville, FL 32604, United States
Shaaya, E., Agricultural Research Organization, The Volcani Center, 50250, Bet Dagan, Israel
Facilitators :
From page:
259
To page:
265
(
Total pages:
7
)
Abstract:
The action of juvenile hormone (JH) and JH mimics have been examined in vitro by utilizing the imaginal disc-derived cell line, IAL-PID2. We have discovered that the cell line was responsive to JH and a variety of JH mimics. The most consistent response obtained in our studies was inhibition of cell proliferation, in the absence of 20-hydroxyecdysone (20E), which characteristically reduces cell proliferation in its own right in this cell line. JH-I, JH-III, methoprene, fenoxycarb, and farnesol significantly inhibited cell proliferation after 3 days of exposure of the cells in vitro to each of the compounds. Linoleic acid controls had no effect on proliferation in the cultures. The cell proliferation assay demonstrates the JH responsiveness of this cell line, but the concentrations of JH required were high compared to the concentrations of 20E needed for inhibition of proliferation in these cells.
Note:
Related Files :
Cell Proliferation
cell stimulation
ecdysterone
hormone action
imaginal disc
Imaginal discs
juvenile hormone
Lepidoptera
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/S0022-1910(99)00178-X
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
22096
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:49
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Scientific Publication
Juvenile hormone and juvenile hormone mimics inhibit proliferation in a lepidopteran imaginal disc cell line
46
Oberlander, H., Center for Medical, Agric. Vet. Entomol., Agric. Res. S., Gainesville, FL 32604, United States
Leach, C.E., Center for Medical, Agric. Vet. Entomol., Agric. Res. S., Gainesville, FL 32604, United States
Shaaya, E., Agricultural Research Organization, The Volcani Center, 50250, Bet Dagan, Israel
Juvenile hormone and juvenile hormone mimics inhibit proliferation in a lepidopteran imaginal disc cell line
The action of juvenile hormone (JH) and JH mimics have been examined in vitro by utilizing the imaginal disc-derived cell line, IAL-PID2. We have discovered that the cell line was responsive to JH and a variety of JH mimics. The most consistent response obtained in our studies was inhibition of cell proliferation, in the absence of 20-hydroxyecdysone (20E), which characteristically reduces cell proliferation in its own right in this cell line. JH-I, JH-III, methoprene, fenoxycarb, and farnesol significantly inhibited cell proliferation after 3 days of exposure of the cells in vitro to each of the compounds. Linoleic acid controls had no effect on proliferation in the cultures. The cell proliferation assay demonstrates the JH responsiveness of this cell line, but the concentrations of JH required were high compared to the concentrations of 20E needed for inhibition of proliferation in these cells.
Scientific Publication
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