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פותח על ידי קלירמאש פתרונות בע"מ -
Lipopolysaccharide challenge of the mammary gland in cows induces nitrosative stress that impairs milk oxidative stability
Year:
2012
Source of publication :
Animal
Authors :
מרין, עוזי
;
.
סילניקוב, ניסים
;
.
ראוך-כהן, עדי
;
.
שפירו, פירה
;
.
Volume :
6
Co-Authors:
Silanikove, N., Biology of Lactation Laboratory, Institute of Animal Science, Volcani Center, P.O. Box 6, Bet Dagan 50250, Israel
Rauch-Cohen, A., Biology of Lactation Laboratory, Institute of Animal Science, Volcani Center, P.O. Box 6, Bet Dagan 50250, Israel
Shapiro, F., Biology of Lactation Laboratory, Institute of Animal Science, Volcani Center, P.O. Box 6, Bet Dagan 50250, Israel
Arieli, A., Department of Animal Science, Faculty of Agricultural, Food and Environmental Sciences, Hebrew University of Jerusalem, Rehovot 76-100, Israel
Merin, U., Food Quality and Safety, Institute of Postharvest and Food Sciences, Volcani Center, P.O. Box 6, Bet Dagan 50250, Israel
Leitner, G., National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, P.O. Box 12, Bet Dagan 50250, Israel
Facilitators :
From page:
1451
To page:
1459
(
Total pages:
9
)
Abstract:
The aim of this work was to study the effects of mastitis induced by intramammary lipopolysaccharide (LPS) challenge on milk oxidative stability, as well as to understand the underlying biochemical processes that cause such changes. LPS challenge was associated with nitric oxide burst from the surrounding mammary epithelial cells and consequently induced nitrosative stress that was induced by the formation of NO2• from nitrite by lactoperoxidase. This response was associated with an ∼3-fold increased formation of hazardous compounds: nitrotyrosines, carbonyls and lipid peroxides. We sustained the involvement of xanthine oxidase as a major source of hydrogen peroxide. In consistent with previous findings, catalase has been shown to play a major role in modulating the nitrosative stress by oxidizing nitrite to nitrate. The current hygienic quality criteria cannot detect mixing of low-quality milk, such as milk with high somatic cells, and nitrite with high-quality milk. Thus, development of an improved quality control methodology may be important for the production of high-quality milk. © The Animal Consortium 2011.
Note:
Related Files :
Animal
Animals
cattle
chemistry
drug effect
Female
Mastitis, Bovine
metabolism
Microbiology
milk
secretion (process)
עוד תגיות
תוכן קשור
More details
DOI :
10.1017/S1751731112000201
Article number:
0
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
22417
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:51
You may also be interested in
Scientific Publication
Lipopolysaccharide challenge of the mammary gland in cows induces nitrosative stress that impairs milk oxidative stability
6
Silanikove, N., Biology of Lactation Laboratory, Institute of Animal Science, Volcani Center, P.O. Box 6, Bet Dagan 50250, Israel
Rauch-Cohen, A., Biology of Lactation Laboratory, Institute of Animal Science, Volcani Center, P.O. Box 6, Bet Dagan 50250, Israel
Shapiro, F., Biology of Lactation Laboratory, Institute of Animal Science, Volcani Center, P.O. Box 6, Bet Dagan 50250, Israel
Arieli, A., Department of Animal Science, Faculty of Agricultural, Food and Environmental Sciences, Hebrew University of Jerusalem, Rehovot 76-100, Israel
Merin, U., Food Quality and Safety, Institute of Postharvest and Food Sciences, Volcani Center, P.O. Box 6, Bet Dagan 50250, Israel
Leitner, G., National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, P.O. Box 12, Bet Dagan 50250, Israel
Lipopolysaccharide challenge of the mammary gland in cows induces nitrosative stress that impairs milk oxidative stability
The aim of this work was to study the effects of mastitis induced by intramammary lipopolysaccharide (LPS) challenge on milk oxidative stability, as well as to understand the underlying biochemical processes that cause such changes. LPS challenge was associated with nitric oxide burst from the surrounding mammary epithelial cells and consequently induced nitrosative stress that was induced by the formation of NO2• from nitrite by lactoperoxidase. This response was associated with an ∼3-fold increased formation of hazardous compounds: nitrotyrosines, carbonyls and lipid peroxides. We sustained the involvement of xanthine oxidase as a major source of hydrogen peroxide. In consistent with previous findings, catalase has been shown to play a major role in modulating the nitrosative stress by oxidizing nitrite to nitrate. The current hygienic quality criteria cannot detect mixing of low-quality milk, such as milk with high somatic cells, and nitrite with high-quality milk. Thus, development of an improved quality control methodology may be important for the production of high-quality milk. © The Animal Consortium 2011.
Scientific Publication
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