חיפוש מתקדם
תחביר
חפש...
הספר "אוצר וולקני"
אודות
תנאי שימוש
ניהול
קהילה:
אסיף מאגר המחקר החקלאי
פותח על ידי קלירמאש פתרונות בע"מ -
Canavanine potentiates the response of insect malpighian tubules to diuretic hormone and cyclic AMP [17]
Year:
1980
Source of publication :
Nature
Authors :
רפאלי, עדה
;
.
Volume :
283
Co-Authors:
Rafaeli, A., Department of Entomology, Faculty of Agriculture, Hebrew University, Rehovot, Israel
Applebaum, S.W., Department of Entomology, Faculty of Agriculture, Hebrew University, Rehovot, Israel
Facilitators :
From page:
872
To page:
873
(
Total pages:
2
)
Abstract:
Insects regulate the amount of water they excrete via their nalpighian tubules, the degree of stringency depending on the hydration of their diet and on the frequency at which they feed. The excretion of water is controlled by a diuretic hormone, which is released as required into the haemolymph by the corpora cardiaca1,2. Previous reports3-5 have shown that non-protein amino acids, known to be neurotoxic in vertebrates6 as well as in insects7, lead to a disruption of water balance in nsects. However, the exact mode of action of these amino acids has not been elucidated. We report here on preliminary experiments using isolated malpighian tubules of locusts Locusta migratoria migratorioides (R & F)) which 9 show that he non-protein amino acid L-canavanine inhibits fluid secretion in vitro by isolated tubules. Furthermore, when tubules, previously inhibited by canavanine, are subsequently stimulated by exogenous diuretic hormone (methanol extracts of storage lobes of corpora cardiaca1,2) or cyclic AMP (which mimics the action of diuretic hormone1), the stimulation obtained is much greater than that normally expected from diuretic hormone or cyclic AMP. © 1980 Nature Publishing Group.
Note:
Related Files :
animal experiment
arthropod
canavanine
Cyclic AMP
diuretic agent
glomerulus
Kidney
preliminary communication
vasopressin
עוד תגיות
תוכן קשור
More details
DOI :
10.1038/283872a0
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מכתב
;
.
Language:
אנגלית
Editors' remarks:
ID:
23366
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:58
Scientific Publication
Canavanine potentiates the response of insect malpighian tubules to diuretic hormone and cyclic AMP [17]
283
Rafaeli, A., Department of Entomology, Faculty of Agriculture, Hebrew University, Rehovot, Israel
Applebaum, S.W., Department of Entomology, Faculty of Agriculture, Hebrew University, Rehovot, Israel
Canavanine potentiates the response of insect malpighian tubules to diuretic hormone and cyclic AMP [17]
Insects regulate the amount of water they excrete via their nalpighian tubules, the degree of stringency depending on the hydration of their diet and on the frequency at which they feed. The excretion of water is controlled by a diuretic hormone, which is released as required into the haemolymph by the corpora cardiaca1,2. Previous reports3-5 have shown that non-protein amino acids, known to be neurotoxic in vertebrates6 as well as in insects7, lead to a disruption of water balance in nsects. However, the exact mode of action of these amino acids has not been elucidated. We report here on preliminary experiments using isolated malpighian tubules of locusts Locusta migratoria migratorioides (R & F)) which 9 show that he non-protein amino acid L-canavanine inhibits fluid secretion in vitro by isolated tubules. Furthermore, when tubules, previously inhibited by canavanine, are subsequently stimulated by exogenous diuretic hormone (methanol extracts of storage lobes of corpora cardiaca1,2) or cyclic AMP (which mimics the action of diuretic hormone1), the stimulation obtained is much greater than that normally expected from diuretic hormone or cyclic AMP. © 1980 Nature Publishing Group.
Scientific Publication
נגישות
menu      
You may also be interested in