חיפוש מתקדם
תחביר
חפש...
הספר "אוצר וולקני"
אודות
תנאי שימוש
ניהול
קהילה:
אסיף מאגר המחקר החקלאי
פותח על ידי קלירמאש פתרונות בע"מ -
Calcium metabolism in birds: computer simulation of response to 1,25-dihydroxycholecalciferol.
Year:
1984
Source of publication :
The American journal of physiology
Authors :
בר, אריה
;
.
הורויץ, שמואל (בעלי חיים)
;
.
טלפז, חובב
;
.
פישמן, ס'
;
.
Volume :
15
Co-Authors:
Hurwitz, S.
Fishman, S.
Bar, A.
Talpaz, H.
Facilitators :
From page:
684
To page:
687
(
Total pages:
4
)
Abstract:
A simulation model of calcium metabolism in the chick has been used to evaluate the response of the systems that regulate plasma calcium to a continuous input of 1,25-dihydroxycholecalciferol [1,25(OH)2D3] from the intestine. The results of simulation showed that the concentration of the vitamin D metabolite in the intestine increased during the first 24 h and thereafter decreased slightly due to suppression of endogenous hormone production. Metabolite accumulation was accompanied by an increase in calcium absorption, with a lag period of about 4 h. Most of the increase in absorbed calcium was excreted in the urine, with a lesser change in net bone calcium uptake. Plasma calcium increased with time, in proportion to the intake of the exogenous hormone. The validity of the predicted steady-state plasma calcium levels, and bone and kidney calcium flows, is discussed. The results of the simulation demonstrate the importance of the vitamin D-intestinal axis in regulation of plasma calcium.
Note:
Related Files :
Animal
article
Blood
calcitriol
calcium
chicken
Chickens
homeostasis
metabolism
Models, Biological
עוד תגיות
תוכן קשור
More details
DOI :
Article number:
0
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:

Pages: R684-R687

ID:
23994
Last updated date:
21/08/2022 07:45
Creation date:
17/04/2018 00:04
Scientific Publication
Calcium metabolism in birds: computer simulation of response to 1,25-dihydroxycholecalciferol.
15
Hurwitz, S.
Fishman, S.
Bar, A.
Talpaz, H.
Calcium metabolism in birds: computer simulation of response to 1,25-dihydroxycholecalciferol.
A simulation model of calcium metabolism in the chick has been used to evaluate the response of the systems that regulate plasma calcium to a continuous input of 1,25-dihydroxycholecalciferol [1,25(OH)2D3] from the intestine. The results of simulation showed that the concentration of the vitamin D metabolite in the intestine increased during the first 24 h and thereafter decreased slightly due to suppression of endogenous hormone production. Metabolite accumulation was accompanied by an increase in calcium absorption, with a lag period of about 4 h. Most of the increase in absorbed calcium was excreted in the urine, with a lesser change in net bone calcium uptake. Plasma calcium increased with time, in proportion to the intake of the exogenous hormone. The validity of the predicted steady-state plasma calcium levels, and bone and kidney calcium flows, is discussed. The results of the simulation demonstrate the importance of the vitamin D-intestinal axis in regulation of plasma calcium.
Scientific Publication
נגישות
menu      
You may also be interested in