חיפוש מתקדם
Lipids
Svoboda, J.A., Insect Neurobiology and Hormone Laboratory, USDA, ARS, PSI, Bldg. 467, BARC-East, Beltsville, 20705-2350, MD, United States
Weirich, G.F., Insect Neurobiology and Hormone Laboratory, USDA, ARS, PSI, Bldg. 467, BARC-East, Beltsville, 20705-2350, MD, United States
A number of intermediates involved in the dealkylation and conversion of the major C28 and C29 phytosterols to cholesterol in insects were first isolated and identified in studies with the tobacco hornworm, Manduca sexta, carried out in our laboratory. We also investigated the effects of a variety of known sterol metabolism inhibitors in Manduca, particularly those affecting the Δ24-sterol reductase enzyme, and synthesized and tested a number of new inhibitors as well. In-depth studies of ecdysteroids in Manduca during embryogenesis and during pupal-adult development provided new information on molting hormone content, biosynthesis, and metabolism. In addition, this insect has been utilized in the study of three specific enzyme systems of ecdysteroid metabolism, namely 20-monooxygenase, 3-epimerase, and phosphotransferase, which are critical to activation and deactivation of molting hormones in insects. © 1995 American Oil Chemists' Society.
פותח על ידי קלירמאש פתרונות בע"מ -
הספר "אוצר וולקני"
אודות
תנאי שימוש
Sterol metabolism in the tobacco hornworm, Manduca sexta-A review
30
Svoboda, J.A., Insect Neurobiology and Hormone Laboratory, USDA, ARS, PSI, Bldg. 467, BARC-East, Beltsville, 20705-2350, MD, United States
Weirich, G.F., Insect Neurobiology and Hormone Laboratory, USDA, ARS, PSI, Bldg. 467, BARC-East, Beltsville, 20705-2350, MD, United States
Sterol metabolism in the tobacco hornworm, Manduca sexta-A review
A number of intermediates involved in the dealkylation and conversion of the major C28 and C29 phytosterols to cholesterol in insects were first isolated and identified in studies with the tobacco hornworm, Manduca sexta, carried out in our laboratory. We also investigated the effects of a variety of known sterol metabolism inhibitors in Manduca, particularly those affecting the Δ24-sterol reductase enzyme, and synthesized and tested a number of new inhibitors as well. In-depth studies of ecdysteroids in Manduca during embryogenesis and during pupal-adult development provided new information on molting hormone content, biosynthesis, and metabolism. In addition, this insect has been utilized in the study of three specific enzyme systems of ecdysteroid metabolism, namely 20-monooxygenase, 3-epimerase, and phosphotransferase, which are critical to activation and deactivation of molting hormones in insects. © 1995 American Oil Chemists' Society.
Scientific Publication
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