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פותח על ידי קלירמאש פתרונות בע"מ -
Deoxyribonucleic acid polymerase of wild type and phosphonoacetic acid resistant mutant of herpes simplex virus
Year:
1978
Authors :
צ'חנובסקי, נור
;
.
Volume :
13
Co-Authors:
Fridlender, B., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Chejanovsky, N., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Becker, Y., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Facilitators :
From page:
124
To page:
127
(
Total pages:
4
)
Abstract:
The phosphonoacetic acid (PAA)-susceptible deoxyribonucleic acid (DNA) polymerase of herpes simplex virus type 1 was partially purified and isolated in sucrose gradients and on double-strand DNA cellulose columns. The DNA polymerase isolated from cells infected with the PAA-resistant mutant had the same molecular weight as the wild- type enzyme (140,000 to 149,000) but was consistently more resistant to PAA.
Note:
Related Files :
DNA-Directed DNA Polymerase
drug resistance
mutation
phosphonoacetic acid
Simplexvirus
virus DNA
virus infection
עוד תגיות
תוכן קשור
More details
DOI :
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
24423
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:07
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Scientific Publication
Deoxyribonucleic acid polymerase of wild type and phosphonoacetic acid resistant mutant of herpes simplex virus
13
Fridlender, B., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Chejanovsky, N., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Becker, Y., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Deoxyribonucleic acid polymerase of wild type and phosphonoacetic acid resistant mutant of herpes simplex virus
The phosphonoacetic acid (PAA)-susceptible deoxyribonucleic acid (DNA) polymerase of herpes simplex virus type 1 was partially purified and isolated in sucrose gradients and on double-strand DNA cellulose columns. The DNA polymerase isolated from cells infected with the PAA-resistant mutant had the same molecular weight as the wild- type enzyme (140,000 to 149,000) but was consistently more resistant to PAA.
Scientific Publication
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