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פותח על ידי קלירמאש פתרונות בע"מ -
Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine
Year:
1993
Source of publication :
The Lancet
Authors :
קנר, יוסף
;
.
Volume :
341
Co-Authors:
Frankel, E.N., Lipid Research Group, University of California, Mrak Hall, Davis, CA 95616, United States
German, J.B., Lipid Research Group, University of California, Mrak Hall, Davis, CA 95616, United States
Kinsella, J.E., Lipid Research Group, University of California, Mrak Hall, Davis, CA 95616, United States
Parks, E., Department of Nutrition, University of California, Davis, Canada
Kanner, J., Volcani Center, Bet Dagan, Israel
Facilitators :
From page:
454
To page:
457
(
Total pages:
4
)
Abstract:
The "French paradox" (apparent compatibility of a high fat diet with a low incidence of coronary atherosclerosis) has been attributed to the regular drinking of red wine. However, the alcohol content of wine may not be the sole explanation for this protection. Red wine also contains phenolic compounds, and the antioxidant properties of these may have an important role. In in-vitro studies with phenolic substances in red wine and normal human low-density lipoprotein (LDL) we found that red wine inhibits the coppercatalysed oxidation of LDL. Wine diluted 1000-fold containing 10 μmol/L total phenolics inhibited LDL oxidation significantly more than α-tocopherol. Our findings show that the non-alcoholic components of red wine have potent antioxidant properties toward oxidation of human LDL. © 1993.
Note:
Related Files :
Atherosclerosis
Coronary Artery Disease
In vitro
Lipoproteins, LDL
oxidation
phenol
phenols
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/0140-6736(93)90206-V
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
24558
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:08
Scientific Publication
Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine
341
Frankel, E.N., Lipid Research Group, University of California, Mrak Hall, Davis, CA 95616, United States
German, J.B., Lipid Research Group, University of California, Mrak Hall, Davis, CA 95616, United States
Kinsella, J.E., Lipid Research Group, University of California, Mrak Hall, Davis, CA 95616, United States
Parks, E., Department of Nutrition, University of California, Davis, Canada
Kanner, J., Volcani Center, Bet Dagan, Israel
Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine
The "French paradox" (apparent compatibility of a high fat diet with a low incidence of coronary atherosclerosis) has been attributed to the regular drinking of red wine. However, the alcohol content of wine may not be the sole explanation for this protection. Red wine also contains phenolic compounds, and the antioxidant properties of these may have an important role. In in-vitro studies with phenolic substances in red wine and normal human low-density lipoprotein (LDL) we found that red wine inhibits the coppercatalysed oxidation of LDL. Wine diluted 1000-fold containing 10 μmol/L total phenolics inhibited LDL oxidation significantly more than α-tocopherol. Our findings show that the non-alcoholic components of red wine have potent antioxidant properties toward oxidation of human LDL. © 1993.
Scientific Publication
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