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פותח על ידי קלירמאש פתרונות בע"מ -
Glucose metabolism in the common carp (Cyprinus carpio L.): the effects of cobalt and chromium
Year:
1989
Source of publication :
Aquaculture (source)
Authors :
חפר, בלפור
;
.
Volume :
76
Co-Authors:
Hertz, Y., The Hebrew University of Jerusalem, Department of Biochemistry and Human Nutrition, Rehovot, 76100, Israel
Madar, Z., The Hebrew University of Jerusalem, Department of Biochemistry and Human Nutrition, Rehovot, 76100, Israel
Hepher, B., Agricultural Research Organization, Fish and Aquaculture Research Station, Israel
Gertler, A., The Hebrew University of Jerusalem, Department of Biochemistry and Human Nutrition, Rehovot, 76100, Israel
Facilitators :
From page:
255
To page:
267
(
Total pages:
13
)
Abstract:
The basal glucose levels in carp plasma are in the same range as in mammals. Glucose tolerance tests in fish resulted in prolonged hyperglycemia with disposal rates resembling the diabetic state in mammals. Increasing doses of glucose and various physiological conditions had little effect on glucose disposal rates, suggesting a low sensitivity of insulin towards glucose levels. High rates of gluconeogenesis from 14C alanine were observed in starved fish and in fish fed a high-protein diet. The transformation of the amino acid to glucose via organic acid intermediates revealed a sensitive control of this pathway, probably at the substrate level. Treatment with cobalt or chromium salts improved glucose utilization and inhibited gluconeogenesis, most likely by modulating the endogenous insulin activity. In preliminary studies, cobalt also increased the incorporation of labelled amino acid into fish protein. These results might indicate a protein-sparing effect, thereby allowing a reduction in the protein levels in the fish diet while increasing the levels of these minerals in the diet. © 1989.
Note:
Related Files :
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/0044-8486(89)90079-3
Article number:
0
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
24868
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:10
Scientific Publication
Glucose metabolism in the common carp (Cyprinus carpio L.): the effects of cobalt and chromium
76
Hertz, Y., The Hebrew University of Jerusalem, Department of Biochemistry and Human Nutrition, Rehovot, 76100, Israel
Madar, Z., The Hebrew University of Jerusalem, Department of Biochemistry and Human Nutrition, Rehovot, 76100, Israel
Hepher, B., Agricultural Research Organization, Fish and Aquaculture Research Station, Israel
Gertler, A., The Hebrew University of Jerusalem, Department of Biochemistry and Human Nutrition, Rehovot, 76100, Israel
Glucose metabolism in the common carp (Cyprinus carpio L.): the effects of cobalt and chromium
The basal glucose levels in carp plasma are in the same range as in mammals. Glucose tolerance tests in fish resulted in prolonged hyperglycemia with disposal rates resembling the diabetic state in mammals. Increasing doses of glucose and various physiological conditions had little effect on glucose disposal rates, suggesting a low sensitivity of insulin towards glucose levels. High rates of gluconeogenesis from 14C alanine were observed in starved fish and in fish fed a high-protein diet. The transformation of the amino acid to glucose via organic acid intermediates revealed a sensitive control of this pathway, probably at the substrate level. Treatment with cobalt or chromium salts improved glucose utilization and inhibited gluconeogenesis, most likely by modulating the endogenous insulin activity. In preliminary studies, cobalt also increased the incorporation of labelled amino acid into fish protein. These results might indicate a protein-sparing effect, thereby allowing a reduction in the protein levels in the fish diet while increasing the levels of these minerals in the diet. © 1989.
Scientific Publication
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