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פותח על ידי קלירמאש פתרונות בע"מ -
Maximum likelihood estimation of quantitative trait loci parameters with the aid of genetic markers using a standard statistical package
Year:
1994
Source of publication :
bioinformatics (source)
Authors :
ולר, יהודה
;
.
Volume :
10
Co-Authors:
Elkind, Y., Faculty of Agriculture, The Hebrew University, Rehovot 76100, Israel
Nir, B., Faculty of Agriculture, The Hebrew University, Rehovot 76100, Israel
Weller, J.I., Faculty of Agriculture, The Hebrew University, Rehovot 76100, Israel, Institute of Animal Sciences, ARO, Volcam Center, Bet Dagan 50250, Israel
Facilitators :
From page:
513
To page:
517
(
Total pages:
5
)
Abstract:
Consistent parameter estimates of quantitative trait loci linked to genetic markers can be derived by maximum likelihood methodology. For many experimental designs of interest, parameter estimates and their standard errors can be obtained by program LE of BMDP, which uses the Newton-Raphson method of iteration. Program LE was tested on data simulated for a backcross between two inbred lines. A single quantitative trait locus linked to either one or two genetic markers was simulated. Convergence was rapid, and computing and programming time were insignificant. All parameter estimates were within the expected bounds. Many different designs can be readily analyzed. © 1994 Oxford University Press.
Note:
Related Files :
breeding
chromosome mapping
computer program
computer simulation
Confidence Intervals
genetic markers
Models, Genetic
quantitative trait
עוד תגיות
תוכן קשור
More details
DOI :
10.1093/bioinformatics/10.5.513
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
25346
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:14
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Scientific Publication
Maximum likelihood estimation of quantitative trait loci parameters with the aid of genetic markers using a standard statistical package
10
Elkind, Y., Faculty of Agriculture, The Hebrew University, Rehovot 76100, Israel
Nir, B., Faculty of Agriculture, The Hebrew University, Rehovot 76100, Israel
Weller, J.I., Faculty of Agriculture, The Hebrew University, Rehovot 76100, Israel, Institute of Animal Sciences, ARO, Volcam Center, Bet Dagan 50250, Israel
Maximum likelihood estimation of quantitative trait loci parameters with the aid of genetic markers using a standard statistical package
Consistent parameter estimates of quantitative trait loci linked to genetic markers can be derived by maximum likelihood methodology. For many experimental designs of interest, parameter estimates and their standard errors can be obtained by program LE of BMDP, which uses the Newton-Raphson method of iteration. Program LE was tested on data simulated for a backcross between two inbred lines. A single quantitative trait locus linked to either one or two genetic markers was simulated. Convergence was rapid, and computing and programming time were insignificant. All parameter estimates were within the expected bounds. Many different designs can be readily analyzed. © 1994 Oxford University Press.
Scientific Publication
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