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פותח על ידי קלירמאש פתרונות בע"מ -
Expression of the rat myosin light-chain 2 gene in transgenic mice: stage specificity, developmental regulation, and interrelation with the endogenous gene.
Year:
1988
Source of publication :
Molecular and Cellular Biology
Authors :
דקל, יצחק
;
.
יופה, אולה
;
.
שני, משה
;
.
Volume :
8
Co-Authors:
Shani, M., Department of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Dekel, I., Department of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Yoffe, O., Department of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Facilitators :
From page:
1006
To page:
1009
(
Total pages:
4
)
Abstract:
The expression of the rat skeletal myosin light-chain 2 gene in two transgenic strains was tissue specific and stage specific. However, the temporal regulation during development of the transgene was different from that of the endogenous gene. Surprisingly, in one strain, the expression of the transgene was associated with a significant down-regulation of the endogenous gene. The possible mechanisms to account for the suppression of the endogenous gene and the potential implications of this suppression are discussed.
Note:
Related Files :
Animal
Cell Division
Genetics
metabolism
mice
Myosin Subfragments
RNA
עוד תגיות
תוכן קשור
More details
DOI :
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
25650
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:16
Scientific Publication
Expression of the rat myosin light-chain 2 gene in transgenic mice: stage specificity, developmental regulation, and interrelation with the endogenous gene.
8
Shani, M., Department of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Dekel, I., Department of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Yoffe, O., Department of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Expression of the rat myosin light-chain 2 gene in transgenic mice: stage specificity, developmental regulation, and interrelation with the endogenous gene.
The expression of the rat skeletal myosin light-chain 2 gene in two transgenic strains was tissue specific and stage specific. However, the temporal regulation during development of the transgene was different from that of the endogenous gene. Surprisingly, in one strain, the expression of the transgene was associated with a significant down-regulation of the endogenous gene. The possible mechanisms to account for the suppression of the endogenous gene and the potential implications of this suppression are discussed.
Scientific Publication
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