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פותח על ידי קלירמאש פתרונות בע"מ -
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions
Year:
1985
Source of publication :
Science
Authors :
גדעוני, דוד
;
.
Volume :
230
Co-Authors:
Gidoni, D., Department of Biochemistry, University of California, Berkeley, CA 94720, United States
Kadonaga, J.T., Department of Biochemistry, University of California, Berkeley, CA 94720, United States
Barrera-Saldana, H., Department of Biochemistry, University of California, Berkeley, CA 94720, United States
Takahashi, K.
Chambon, P.
Tjian, R.
Facilitators :
From page:
511
To page:
517
(
Total pages:
7
)
Abstract:
The 21-base pair repeat elements of the SV40 promoter contain six tandem copies of the GGGCGG hexanucleotide (GC-box), each of which can bind, with varying affinity, to the cellular transcription factor, Sp1. In vitro SV40 early RNA synthesis is mediated by interaction of Sp1 with GC-boxes I, II, and III, whereas transcription in the late direction is mediated by binding to GC-boxes III, V, and VI.
Note:
Related Files :
Base Sequence
Deoxyribonuclease I
Heredity
mutation
Templates, Genetic
עוד תגיות
תוכן קשור
More details
DOI :
10.1126/science.2996137
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
25805
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:17
Scientific Publication
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions
230
Gidoni, D., Department of Biochemistry, University of California, Berkeley, CA 94720, United States
Kadonaga, J.T., Department of Biochemistry, University of California, Berkeley, CA 94720, United States
Barrera-Saldana, H., Department of Biochemistry, University of California, Berkeley, CA 94720, United States
Takahashi, K.
Chambon, P.
Tjian, R.
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions
The 21-base pair repeat elements of the SV40 promoter contain six tandem copies of the GGGCGG hexanucleotide (GC-box), each of which can bind, with varying affinity, to the cellular transcription factor, Sp1. In vitro SV40 early RNA synthesis is mediated by interaction of Sp1 with GC-boxes I, II, and III, whereas transcription in the late direction is mediated by binding to GC-boxes III, V, and VI.
Scientific Publication
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