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פותח על ידי קלירמאש פתרונות בע"מ -
An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design
Year:
2004
Source of publication :
Theoretical and Applied Genetics
Authors :
ולר, יהודה
;
.
Volume :
109
Co-Authors:
Weller, J.I., Institute of Animal Sciences, Agricultural Research Organization, Volcani Center, P.O. Box 6, Bet Dagan, 50250, Israel
Soller, M., Department of Genetics, Hebrew University of Jerusalem, Jerusalem 91904, Israel
Facilitators :
From page:
1224
To page:
1229
(
Total pages:
6
)
Abstract:
Analytical formulae are derived for the confidence interval for location of a quantitative trait locus (QTL) using a saturated genetic map, as a function of the experimental design, the QTL allele substitution effect, and the number of individuals genotyped and phenotyped. The formulae are derived assuming evenly spaced recombination events, rather than the actual unevenly spaced distribution. The formulae are useful for determining desired sample size when designing a wide variety of QTL mapping experiments, and for evaluating a priori the potential of a given mapping population for defining the location of a QTL. The formulae do not take into account the finite number of recombination events in a given sample. © Springer-Verlag 2004.
Note:
Related Files :
Animal
Animals
chromosome map
chromosome mapping
genetic engineering
genetic recombination
Sampling
עוד תגיות
תוכן קשור
More details
DOI :
10.1007/s00122-004-1664-2
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
26506
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:23
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Scientific Publication
An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design
109
Weller, J.I., Institute of Animal Sciences, Agricultural Research Organization, Volcani Center, P.O. Box 6, Bet Dagan, 50250, Israel
Soller, M., Department of Genetics, Hebrew University of Jerusalem, Jerusalem 91904, Israel
An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design
Analytical formulae are derived for the confidence interval for location of a quantitative trait locus (QTL) using a saturated genetic map, as a function of the experimental design, the QTL allele substitution effect, and the number of individuals genotyped and phenotyped. The formulae are derived assuming evenly spaced recombination events, rather than the actual unevenly spaced distribution. The formulae are useful for determining desired sample size when designing a wide variety of QTL mapping experiments, and for evaluating a priori the potential of a given mapping population for defining the location of a QTL. The formulae do not take into account the finite number of recombination events in a given sample. © Springer-Verlag 2004.
Scientific Publication
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