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פותח על ידי קלירמאש פתרונות בע"מ -
Signatures of contemporary selection in the Israeli Holstein dairy cattle
Year:
2012
Source of publication :
Animal Genetics
Authors :
אוליאל, שי
;
.
ולר, יהודה
;
.
סרוסי, אייל
;
.
רון, מיכה
;
.
שיראק, אנדרי
;
.
Volume :
43
Co-Authors:
Glick, G., Robert H. Smith Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot 76100, Israel
Shirak, A., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan 50250, Israel
Uliel, S., Israel Cattle Breeders Association, Caesaria Industrial Park, Caesaria 38900, Israel
Zeron, Y., Sion AI Institute, Shikmim 79800, Israel
Ezra, E., Israel Cattle Breeders Association, Caesaria Industrial Park, Caesaria 38900, Israel
Seroussi, E., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan 50250, Israel
Ron, M., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan 50250, Israel
Weller, J.I., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan 50250, Israel
Facilitators :
From page:
45
To page:
55
(
Total pages:
11
)
Abstract:
Strong selection in the Israeli Holstein dairy cattle population over the last three decades should have left clear signatures of selection. Two experimental approaches were applied to detect evidence of contemporary selection based on the 54K BeadChip genotypes of ~1000 Israeli Holstein bulls: (i) the long-range haplotype test, which searches for structural evidence resulting from selective sweep, and (ii) direct analysis of the changes in haplotypes frequencies over time combined with linkage disequilibrium blocks haplotype-based association analysis. Ten traits were analyzed: the PD07 Israeli selection index, milk, milk fat, % fat, milk protein, % protein, somatic cell score, female fertility, milk production persistency and herd life. The long-range haplotype test detected ~15% of the 3288 haplotypes that showed significant positive frequency trends (P < 0.05) and was significantly correlated with the substitution effects of the haplotypes and the selection intensities for the different traits. Thirty signatures of recent selection, which correspond to both approaches and affect the Israeli PD07 selection index, were identified on 17 of the 29 autosomes. The second experimental approach also was used to estimate the selection intensity of the different traits. The correlation between the selection intensities for the traits analyzed, derived from changes in haplotype frequencies in the population of bulls, and those derived from trait-based analysis of the cow population was 0.93 over all traits. Thus, the changes in haplotypes frequencies in the bulls' population accurately estimate genetic trends in the general cow population and can be used to detect signatures of recent selection. © 2012 Stichting International Foundation for Animal Genetics.
Note:
Related Files :
Animal
Animals
breeding
cattle
dairy cattle
Female
Genetics
Israel
lactation
Male
milk
עוד תגיות
תוכן קשור
More details
DOI :
10.1111/j.1365-2052.2012.02348.x
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
26733
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:25
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Scientific Publication
Signatures of contemporary selection in the Israeli Holstein dairy cattle
43
Glick, G., Robert H. Smith Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot 76100, Israel
Shirak, A., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan 50250, Israel
Uliel, S., Israel Cattle Breeders Association, Caesaria Industrial Park, Caesaria 38900, Israel
Zeron, Y., Sion AI Institute, Shikmim 79800, Israel
Ezra, E., Israel Cattle Breeders Association, Caesaria Industrial Park, Caesaria 38900, Israel
Seroussi, E., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan 50250, Israel
Ron, M., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan 50250, Israel
Weller, J.I., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan 50250, Israel
Signatures of contemporary selection in the Israeli Holstein dairy cattle
Strong selection in the Israeli Holstein dairy cattle population over the last three decades should have left clear signatures of selection. Two experimental approaches were applied to detect evidence of contemporary selection based on the 54K BeadChip genotypes of ~1000 Israeli Holstein bulls: (i) the long-range haplotype test, which searches for structural evidence resulting from selective sweep, and (ii) direct analysis of the changes in haplotypes frequencies over time combined with linkage disequilibrium blocks haplotype-based association analysis. Ten traits were analyzed: the PD07 Israeli selection index, milk, milk fat, % fat, milk protein, % protein, somatic cell score, female fertility, milk production persistency and herd life. The long-range haplotype test detected ~15% of the 3288 haplotypes that showed significant positive frequency trends (P < 0.05) and was significantly correlated with the substitution effects of the haplotypes and the selection intensities for the different traits. Thirty signatures of recent selection, which correspond to both approaches and affect the Israeli PD07 selection index, were identified on 17 of the 29 autosomes. The second experimental approach also was used to estimate the selection intensity of the different traits. The correlation between the selection intensities for the traits analyzed, derived from changes in haplotype frequencies in the population of bulls, and those derived from trait-based analysis of the cow population was 0.93 over all traits. Thus, the changes in haplotypes frequencies in the bulls' population accurately estimate genetic trends in the general cow population and can be used to detect signatures of recent selection. © 2012 Stichting International Foundation for Animal Genetics.
Scientific Publication
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