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קהילה:
אסיף מאגר המחקר החקלאי
פותח על ידי קלירמאש פתרונות בע"מ -
Carbohydrate metabolism of hepatocytes from starved Japanese quail
Year:
1982
Authors :
ריזנפלד, גד
;
.
Volume :
213
Co-Authors:
Golden, S., Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States
Riesenfeld, G., Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States
Katz, J., Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States
Facilitators :
From page:
118
To page:
126
(
Total pages:
9
)
Abstract:
Hepatocytes were isolated from livers of mature male and female starved Japanese quail (Coturnix coturnix japonica). The hepatocytes take up lactate and dihydroxyacetone extensively, and have a very high rate of glucose synthesis from these substrates. Fructose uptake and incorporation into glucose is much less. Pyruvate and alanine are taken up extensively, but form little glucose. There is negligible lipogenesis in cells of starved quail. Alanine increases up to 10-fold incorporation of 3HOH and 14C from several substrates into fatty acids, but it remains insignificant as compared to lipogenesis by cells of fed quail. There is little utilization of glucose, even in the presence of alanine, in marked contrast to hepatocytes from fed quail. However, glucose is phosphorylated at high rates, but most of the glucose 6-phosphate is recycled to glucose. There is a marked difference in the metabolism of polyols between the sexes. Glycerol, xylitol, and sorbitol are converted nearly quantitatively into glucose by hepatocytes of starved female quail. In cells of starved males, the uptake of polyols is higher, but conversion to glucose less efficient. In cells of starved male quail, alanine markedly stimulates the uptake of glycerol and xylitol and their conversion to glucose, but has no effect on sorbitol metabolism. In cells of female quail, alanine is without a significant effect on polyol metabolism. © 1982.
Note:
Related Files :
Animal
Carbohydrate
carbohydrates
Female
gluconeogenesis
lactic acid
lipid
Lipids
liver
Male
metabolism
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/0003-9861(82)90446-5
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
26751
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:25
Scientific Publication
Carbohydrate metabolism of hepatocytes from starved Japanese quail
213
Golden, S., Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States
Riesenfeld, G., Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States
Katz, J., Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States
Carbohydrate metabolism of hepatocytes from starved Japanese quail
Hepatocytes were isolated from livers of mature male and female starved Japanese quail (Coturnix coturnix japonica). The hepatocytes take up lactate and dihydroxyacetone extensively, and have a very high rate of glucose synthesis from these substrates. Fructose uptake and incorporation into glucose is much less. Pyruvate and alanine are taken up extensively, but form little glucose. There is negligible lipogenesis in cells of starved quail. Alanine increases up to 10-fold incorporation of 3HOH and 14C from several substrates into fatty acids, but it remains insignificant as compared to lipogenesis by cells of fed quail. There is little utilization of glucose, even in the presence of alanine, in marked contrast to hepatocytes from fed quail. However, glucose is phosphorylated at high rates, but most of the glucose 6-phosphate is recycled to glucose. There is a marked difference in the metabolism of polyols between the sexes. Glycerol, xylitol, and sorbitol are converted nearly quantitatively into glucose by hepatocytes of starved female quail. In cells of starved males, the uptake of polyols is higher, but conversion to glucose less efficient. In cells of starved male quail, alanine markedly stimulates the uptake of glycerol and xylitol and their conversion to glucose, but has no effect on sorbitol metabolism. In cells of female quail, alanine is without a significant effect on polyol metabolism. © 1982.
Scientific Publication
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