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פותח על ידי קלירמאש פתרונות בע"מ -
Sensitivity of meiotic yeast cells to ultraviolet light
Year:
1973
Source of publication :
Genetics (מקור פרסום )
Authors :
זלץ, יחיעם
;
.
Volume :
73
Co-Authors:
Simchen, G., Dept. Genet., Univ. Washington, Seattle, Wash. 98195, United States
Salts, Y., Dept. Genet., Univ. Washington, Seattle, Wash. 98195, United States
Pinon, R., Dept. Genet., Univ. Washington, Seattle, Wash. 98195, United States
Facilitators :
From page:
531
To page:
541
(
Total pages:
11
)
Abstract:
Sporulating cells of Saccharomyces cerevisiae show an increasing sensitivity to ultraviolet irradiation. Maximum sensitivity is reached at a time comparable to meiotic prophase. Sensitivity is expressed as reduced sporulation after the irradiation. The uv effect can be efficiently reversed by photoreactivating light. Viability is also more severely affected during premeiotic DNA synthesis and during meiosis than in earlier stages in sporulation. Cells left in sporulation medium after the irradiation show a reduced viability compared with the cells plated immediately after the irradiation. Non sporulating diploids do not acquire sensitivity when exposed to sporulation medium, hence the sensitivity is related to the sporulation process. That meiosis itself is affected, rather than spore formation alone, is evident from experiments in which the uv irradiation interferes with the uncovering of a recessive marker and with commitment to meiosis. It is proposed that during meiotic prophase, the DNA repair system is different from that found in vegetative cells.
Note:
Related Files :
in vitro study
meiosis
radiosensitivity
Saccharomyces cerevisiae
theoretical study
ultraviolet radiation
עוד תגיות
תוכן קשור
More details
DOI :
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
Language:
אנגלית
Editors' remarks:
ID:
26817
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:25
Scientific Publication
Sensitivity of meiotic yeast cells to ultraviolet light
73
Simchen, G., Dept. Genet., Univ. Washington, Seattle, Wash. 98195, United States
Salts, Y., Dept. Genet., Univ. Washington, Seattle, Wash. 98195, United States
Pinon, R., Dept. Genet., Univ. Washington, Seattle, Wash. 98195, United States
Sensitivity of meiotic yeast cells to ultraviolet light
Sporulating cells of Saccharomyces cerevisiae show an increasing sensitivity to ultraviolet irradiation. Maximum sensitivity is reached at a time comparable to meiotic prophase. Sensitivity is expressed as reduced sporulation after the irradiation. The uv effect can be efficiently reversed by photoreactivating light. Viability is also more severely affected during premeiotic DNA synthesis and during meiosis than in earlier stages in sporulation. Cells left in sporulation medium after the irradiation show a reduced viability compared with the cells plated immediately after the irradiation. Non sporulating diploids do not acquire sensitivity when exposed to sporulation medium, hence the sensitivity is related to the sporulation process. That meiosis itself is affected, rather than spore formation alone, is evident from experiments in which the uv irradiation interferes with the uncovering of a recessive marker and with commitment to meiosis. It is proposed that during meiotic prophase, the DNA repair system is different from that found in vegetative cells.
Scientific Publication
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