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פותח על ידי קלירמאש פתרונות בע"מ -
Taste memory: The role of protein synthesis in gustatory cortex
Year:
1993
Source of publication :
Behavioral and Neural Biology
Authors :
מאירי, נעם
;
.
Volume :
59
Co-Authors:
Rosenblum, K., Department of Neurobiology, Weizmann Institute of Science, Rehovot, 76100, Israel
Meiri, N., Department of Neurobiology, Weizmann Institute of Science, Rehovot, 76100, Israel
Dudai, Y., Department of Neurobiology, Weizmann Institute of Science, Rehovot, 76100, Israel
Facilitators :
From page:
49
To page:
56
(
Total pages:
8
)
Abstract:
Application of the protein synthesis inhibitor anisomycin to the rat gustatory cortex before and during training impairs conditioned taste aversion (CTA) to saccharin. No behavioral impairment is observed if the inhibitor is applied to an adjacent cortical area or to one cortical hemisphere only. The consumption of saccharin and of total fluid, as well as behavioral recognition of saccharin, is not affected. Preexposure of rats to saccharin several days before training markedly inhibits CTA to that taste. Injection of anisomycin to the gustatory cortex immediately prior to the preexposure period attenuates the latent inhibition. These results suggest that protein synthesis in the gustatory cortex is required for normal acquisition of the memory of taste. © 1978 Academic Press, Inc.
Note:
Related Files :
Animal
animal experiment
Cerebral Cortex
Male
memory consolidation
protein synthesis inhibition
recognition
taste
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/0163-1047(93)91145-D
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
27496
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:31
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Scientific Publication
Taste memory: The role of protein synthesis in gustatory cortex
59
Rosenblum, K., Department of Neurobiology, Weizmann Institute of Science, Rehovot, 76100, Israel
Meiri, N., Department of Neurobiology, Weizmann Institute of Science, Rehovot, 76100, Israel
Dudai, Y., Department of Neurobiology, Weizmann Institute of Science, Rehovot, 76100, Israel
Taste memory: The role of protein synthesis in gustatory cortex
Application of the protein synthesis inhibitor anisomycin to the rat gustatory cortex before and during training impairs conditioned taste aversion (CTA) to saccharin. No behavioral impairment is observed if the inhibitor is applied to an adjacent cortical area or to one cortical hemisphere only. The consumption of saccharin and of total fluid, as well as behavioral recognition of saccharin, is not affected. Preexposure of rats to saccharin several days before training markedly inhibits CTA to that taste. Injection of anisomycin to the gustatory cortex immediately prior to the preexposure period attenuates the latent inhibition. These results suggest that protein synthesis in the gustatory cortex is required for normal acquisition of the memory of taste. © 1978 Academic Press, Inc.
Scientific Publication
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