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פותח על ידי קלירמאש פתרונות בע"מ -
Environmental effects on longevity in the male rat: Exercise, mating, castration and restricted feeding
Year:
1976
Source of publication :
Experimental Gerontology
Authors :
דרורי, דוד
;
.
פולמן, ישעיהו
;
.
Volume :
11
Co-Authors:
Drori, D., Institute of Animal Science, Agricultural Research Organization, P.O. Box 6, Bet Dagan, Israel
Folman, Y., Institute of Animal Science, Agricultural Research Organization, P.O. Box 6, Bet Dagan, Israel
Facilitators :
From page:
25
To page:
32
(
Total pages:
8
)
Abstract:
Mating increases the longevity of male rats; the hypothesis was tested that this is mainly caused by exercise. Six groups of rats, five of males and one of females, were used. The male groups were: (a) exercised, (b) mated, (c) castrated, (d) underfed and (e) control (untreated). The females (f) were untreated. Fifty-nine sextuplets of littermates (354 rats) were used, 49 to estimate life span and 10 to determine body composition. The mean life span in days was: (a) 859, (b) 840, (c) 817, (d) 885, (e) 727 and (f) 849. The differences between the control males (e) and all the other groups were highly significant (P < 0·01) except for the castrates (P < 0·05). Exercise and mating produced similar survival curves. Mating increased feed intake but greatly reduced the body fat; in sharp contrast, exercise had little effect on body weight, fat content or feed intake. Both exercise and mating significantly reduced the incidence of pneumonia (P < 0·01). Underfed males (d) had a lower incidence of degenerative lesions; their energy retention suggested very great activity. The energy retention of females also suggested more activity than that of the control males. It is suggested that castration moderately prolongs life span because of the low metabolic rate and large body fat stores of castrated males which delay death by inanition during chronic terminal disease. Exercise appeared to be the most decisive and consistent factor prolonging the life span of albino rats; it did so mainly by preventing early deaths. © 1976.
Note:
Related Files :
Animal
body composition
castration
death
exercise
Female
food intake
Male
mating
mice
Rabbits
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/0531-5565(76)90007-3
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
29150
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:44
Scientific Publication
Environmental effects on longevity in the male rat: Exercise, mating, castration and restricted feeding
11
Drori, D., Institute of Animal Science, Agricultural Research Organization, P.O. Box 6, Bet Dagan, Israel
Folman, Y., Institute of Animal Science, Agricultural Research Organization, P.O. Box 6, Bet Dagan, Israel
Environmental effects on longevity in the male rat: Exercise, mating, castration and restricted feeding
Mating increases the longevity of male rats; the hypothesis was tested that this is mainly caused by exercise. Six groups of rats, five of males and one of females, were used. The male groups were: (a) exercised, (b) mated, (c) castrated, (d) underfed and (e) control (untreated). The females (f) were untreated. Fifty-nine sextuplets of littermates (354 rats) were used, 49 to estimate life span and 10 to determine body composition. The mean life span in days was: (a) 859, (b) 840, (c) 817, (d) 885, (e) 727 and (f) 849. The differences between the control males (e) and all the other groups were highly significant (P < 0·01) except for the castrates (P < 0·05). Exercise and mating produced similar survival curves. Mating increased feed intake but greatly reduced the body fat; in sharp contrast, exercise had little effect on body weight, fat content or feed intake. Both exercise and mating significantly reduced the incidence of pneumonia (P < 0·01). Underfed males (d) had a lower incidence of degenerative lesions; their energy retention suggested very great activity. The energy retention of females also suggested more activity than that of the control males. It is suggested that castration moderately prolongs life span because of the low metabolic rate and large body fat stores of castrated males which delay death by inanition during chronic terminal disease. Exercise appeared to be the most decisive and consistent factor prolonging the life span of albino rats; it did so mainly by preventing early deaths. © 1976.
Scientific Publication
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