נגישות
menu      
חיפוש מתקדם
תחביר
חפש...
הספר "אוצר וולקני"
אודות
תנאי שימוש
ניהול
קהילה:
אסיף מאגר המחקר החקלאי
פותח על ידי קלירמאש פתרונות בע"מ -
Insect steroid metabolism
Year:
1978
Source of publication :
Lipids
Authors :
סבובודה, ג'יימס
;
.
Volume :
13
Co-Authors:
Svoboda, J.A., Insect Physiology Laboratory, U.S. Department of Agriculture, Federal Research, Science and Education Administration, Beltsville, 20705, Maryland, United States
Thompson, M.J., Insect Physiology Laboratory, U.S. Department of Agriculture, Federal Research, Science and Education Administration, Beltsville, 20705, Maryland, United States
Robbins, W.E., Insect Physiology Laboratory, U.S. Department of Agriculture, Federal Research, Science and Education Administration, Beltsville, 20705, Maryland, United States
Kaplanis, J.N., Insect Physiology Laboratory, U.S. Department of Agriculture, Federal Research, Science and Education Administration, Beltsville, 20705, Maryland, United States
Facilitators :
From page:
742
To page:
753
(
Total pages:
12
)
Abstract:
Insects are unable to biosynthesize the steroid nucleus and generally require an exogenous source of sterols. Two salient areas of insect steroid metabolism are the dealkylation and conversion of dietary C28 and C29 plant sterols to cholesterol and other C27 sterols, and the biosynthesis and metabolism of the steroidal insect molting hormones. Certain azasteroids and nonsteroidal amines block this conversion of 24-alkyl sterols to cholesterol and/or disrupt molting and development in insects. These inhibitors have served in charting metabolic pathways for steroids in insects and are serving as models in developing selective pesticidal chemicals and chemotherapeutic agents for use against insects and other invertebrate pests and parasites. The mode of action of some of these inhibitors on molting and development has been investigated in vivo and in vitro. Certain of these inhibitors represent a new class of insect hormonal compounds with a novel mode of action-the disruption of molting hormone metabolism. Research on sterol metabolism in insects provides important information on the comparative biochemistry and physiological functions of steroids in living systems. © 1978 American Oil Chemists' Society.
Note:
Related Files :
22,23 dihydroergosterol
animal experiment
cholestanol
insect
Review
sitosterol
sterol
עוד תגיות
תוכן קשור
More details
DOI :
10.1007/BF02533755
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
29530
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:47
Scientific Publication
Insect steroid metabolism
13
Svoboda, J.A., Insect Physiology Laboratory, U.S. Department of Agriculture, Federal Research, Science and Education Administration, Beltsville, 20705, Maryland, United States
Thompson, M.J., Insect Physiology Laboratory, U.S. Department of Agriculture, Federal Research, Science and Education Administration, Beltsville, 20705, Maryland, United States
Robbins, W.E., Insect Physiology Laboratory, U.S. Department of Agriculture, Federal Research, Science and Education Administration, Beltsville, 20705, Maryland, United States
Kaplanis, J.N., Insect Physiology Laboratory, U.S. Department of Agriculture, Federal Research, Science and Education Administration, Beltsville, 20705, Maryland, United States
Insect steroid metabolism
Insects are unable to biosynthesize the steroid nucleus and generally require an exogenous source of sterols. Two salient areas of insect steroid metabolism are the dealkylation and conversion of dietary C28 and C29 plant sterols to cholesterol and other C27 sterols, and the biosynthesis and metabolism of the steroidal insect molting hormones. Certain azasteroids and nonsteroidal amines block this conversion of 24-alkyl sterols to cholesterol and/or disrupt molting and development in insects. These inhibitors have served in charting metabolic pathways for steroids in insects and are serving as models in developing selective pesticidal chemicals and chemotherapeutic agents for use against insects and other invertebrate pests and parasites. The mode of action of some of these inhibitors on molting and development has been investigated in vivo and in vitro. Certain of these inhibitors represent a new class of insect hormonal compounds with a novel mode of action-the disruption of molting hormone metabolism. Research on sterol metabolism in insects provides important information on the comparative biochemistry and physiological functions of steroids in living systems. © 1978 American Oil Chemists' Society.
Scientific Publication
You may also be interested in