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פותח על ידי קלירמאש פתרונות בע"מ -
Effect of protectors on morphofunctional changes in rat kidneys in tourniquet shock
Year:
1992
Authors :
אורלוב, אלה
;
.
Volume :
36
Co-Authors:
Shleikin, A.G., Kafedra Vnutrennikh Boleznej, Sanitarno-Gig. Meditsinskij Institut, Sankt-Peterburg, Russian Federation
Shulutko, B.I., Kafedra Vnutrennikh Boleznej, Sanitarno-Gig. Meditsinskij Institut, Sankt-Peterburg, Russian Federation
Oksman, T.M., Kafedra Vnutrennikh Boleznej, Sanitarno-Gig. Meditsinskij Institut, Sankt-Peterburg, Russian Federation
Orlov, A.V., Kafedra Vnutrennikh Boleznej, Sanitarno-Gig. Meditsinskij Institut, Sankt-Peterburg, Russian Federation
Facilitators :
From page:
36
To page:
37
(
Total pages:
2
)
Abstract:
The protective effect produced on the kidneys in tourniquet shock by thiol agents possessing antioxidant properties (unithiol, cystamine) was compared with that of a preparation of cell capsules of L. bulgaricus (CCLB). Tourniquet shock was modeled under ether Raush anesthesia by applying 8 turns of a rubber tourniquet to the hind limbs for 6 hours. Thirty minutes before removal of the tourniquet animals of the first group were given an injection of 1 ml of physiological solution, animals of the second group - 20 mg/kg of unithol, those of the third group received an injection of 20 mg/kg of cystamine hydrochloride. Animals of the fourth group received 50 mg/kg of CCLB in 1 ml of physiological solution 7 days before the experiment. A marked protective effect of CCLB on the kidneys in tourniquet shock was established. According to the degree of the protective effect on the tissue of kidneys in tourniquet shock, the studied agents come in the following order: CCLB, cystamine, unithiol.
Note:
Related Files :
Animal
animal experiment
bacterial membrane
drug effect
Kidney
Male
Pathology
עוד תגיות
תוכן קשור
More details
DOI :
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
רוסית
Editors' remarks:
ID:
29889
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:50
You may also be interested in
Scientific Publication
Effect of protectors on morphofunctional changes in rat kidneys in tourniquet shock
36
Shleikin, A.G., Kafedra Vnutrennikh Boleznej, Sanitarno-Gig. Meditsinskij Institut, Sankt-Peterburg, Russian Federation
Shulutko, B.I., Kafedra Vnutrennikh Boleznej, Sanitarno-Gig. Meditsinskij Institut, Sankt-Peterburg, Russian Federation
Oksman, T.M., Kafedra Vnutrennikh Boleznej, Sanitarno-Gig. Meditsinskij Institut, Sankt-Peterburg, Russian Federation
Orlov, A.V., Kafedra Vnutrennikh Boleznej, Sanitarno-Gig. Meditsinskij Institut, Sankt-Peterburg, Russian Federation
Effect of protectors on morphofunctional changes in rat kidneys in tourniquet shock
The protective effect produced on the kidneys in tourniquet shock by thiol agents possessing antioxidant properties (unithiol, cystamine) was compared with that of a preparation of cell capsules of L. bulgaricus (CCLB). Tourniquet shock was modeled under ether Raush anesthesia by applying 8 turns of a rubber tourniquet to the hind limbs for 6 hours. Thirty minutes before removal of the tourniquet animals of the first group were given an injection of 1 ml of physiological solution, animals of the second group - 20 mg/kg of unithol, those of the third group received an injection of 20 mg/kg of cystamine hydrochloride. Animals of the fourth group received 50 mg/kg of CCLB in 1 ml of physiological solution 7 days before the experiment. A marked protective effect of CCLB on the kidneys in tourniquet shock was established. According to the degree of the protective effect on the tissue of kidneys in tourniquet shock, the studied agents come in the following order: CCLB, cystamine, unithiol.
Scientific Publication
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