חיפוש מתקדם
Aquaculture (source)
Nitzan, T., Institute of Animal Science, Agricultural Research Organization, Bet Dagan 50250, Israel
Rozenberg, P., Institute of Animal Science, Agricultural Research Organization, Bet Dagan 50250, Israel, Department of Animal Sciences, Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel
Cnaani, A., Institute of Animal Science, Agricultural Research Organization, Bet Dagan 50250, Israel
Nitzan, T., Institute of Animal Science, Agricultural Research Organization, Bet Dagan, Israel
Rozenberg, P., Institute of Animal Science, Agricultural Research Organization, Bet Dagan, Israel, Department of Animal Sciences, Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel
Cnaani, A., Institute of Animal Science, Agricultural Research Organization, Bet Dagan, Israel
Nutrients are absorbed through transporters located in the brush border of intestinal absorptive epithelial cells. These transporters are complexes of proteins that control the uptake or removal of different compounds through cell and organelle membranes. Ingested proteins are catabolized to short-peptide and amino acids, which are absorbed through specified intestinal transporters. Two key complexes in this process are the B0AT (encoded by the SLC6A19 gene) and B0,+AT (encoded by the SLC3A1 and SLC7A9 genes), that transfer neutral and cationic amino acids. This research was conducted in Mozambique tilapia (Oreochromis mossambicus), with the aim of characterizing the dynamic of their expression along different intestinal sections at different time-points after feeding, in different water salinities. Our results demonstrated the dynamic of gene expression patterns along the intestine, with significant salinity effect on the genes encoding to the B0,+AT. Differences in expression levels with time after feeding were found in all three genes, with the highest expression observed at 6h after feeding, in the middle intestine. Some of our results differ from what was expected based on data from mammalian organisms, and with only few previous studies on these transporters in any fish species, this is one of the first steps toward characterization of their regulation in fish. Statement of Relevance: The results can lead to better food utilization. © 2016 Elsevier B.V.
פותח על ידי קלירמאש פתרונות בע"מ -
הספר "אוצר וולקני"
אודות
תנאי שימוש
Differential expression of amino-acid transporters along the intestine of Mozambique tilapia (Oreochromis mossambicus) and the effect of water salinity and time after feeding
472
Nitzan, T., Institute of Animal Science, Agricultural Research Organization, Bet Dagan 50250, Israel
Rozenberg, P., Institute of Animal Science, Agricultural Research Organization, Bet Dagan 50250, Israel, Department of Animal Sciences, Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel
Cnaani, A., Institute of Animal Science, Agricultural Research Organization, Bet Dagan 50250, Israel
Nitzan, T., Institute of Animal Science, Agricultural Research Organization, Bet Dagan, Israel
Rozenberg, P., Institute of Animal Science, Agricultural Research Organization, Bet Dagan, Israel, Department of Animal Sciences, Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel
Cnaani, A., Institute of Animal Science, Agricultural Research Organization, Bet Dagan, Israel
Differential expression of amino-acid transporters along the intestine of Mozambique tilapia (Oreochromis mossambicus) and the effect of water salinity and time after feeding
Nutrients are absorbed through transporters located in the brush border of intestinal absorptive epithelial cells. These transporters are complexes of proteins that control the uptake or removal of different compounds through cell and organelle membranes. Ingested proteins are catabolized to short-peptide and amino acids, which are absorbed through specified intestinal transporters. Two key complexes in this process are the B0AT (encoded by the SLC6A19 gene) and B0,+AT (encoded by the SLC3A1 and SLC7A9 genes), that transfer neutral and cationic amino acids. This research was conducted in Mozambique tilapia (Oreochromis mossambicus), with the aim of characterizing the dynamic of their expression along different intestinal sections at different time-points after feeding, in different water salinities. Our results demonstrated the dynamic of gene expression patterns along the intestine, with significant salinity effect on the genes encoding to the B0,+AT. Differences in expression levels with time after feeding were found in all three genes, with the highest expression observed at 6h after feeding, in the middle intestine. Some of our results differ from what was expected based on data from mammalian organisms, and with only few previous studies on these transporters in any fish species, this is one of the first steps toward characterization of their regulation in fish. Statement of Relevance: The results can lead to better food utilization. © 2016 Elsevier B.V.
Scientific Publication
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