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פותח על ידי קלירמאש פתרונות בע"מ -
Site of bile acid absorption in the rat
Year:
1976
Source of publication :
Lipids
Authors :
הורויץ, שמואל (בעלי חיים)
;
.
Volume :
11
Co-Authors:
Sklan, D., Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel
Budowski, P., Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel
Hurwitz, S., Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel
Facilitators :
From page:
467
To page:
471
(
Total pages:
5
)
Abstract:
Bile acid absorption was measured in the small intestine of the rat using91Y as a nonabsorbed reference substance. Some 50% of the secreted bile acids were absorbed in the proximal half of the small intestine. In situ incubations of ligated intestinal segments into which tauro(14C-carbonyl)cholic acid was introduced confirmed the considerable uptake of bile acids in the jejunum. The in situ experiments indicated that serosal transport is the limiting stage of bile acid absorption in the jejunum but not in the ileum. Increasing bile acid concentrations in the in situ experiments did not affect the percentage disappearance of dose from the jejunum but reduced the percentage mucosal uptake in the ileum. It is concluded that, in the rat, the proximal small intestine is as important in the absorption of bile acids as the distal small intestine. © 1976 American Oil Chemists' Society.
Note:
Related Files :
Animal
bile acid
Bile Acids and Salts
ileum
Intestinal Mucosa
intestine absorption
Male
rat
Taurocholic Acid
taurocholic acid c 14
עוד תגיות
תוכן קשור
More details
DOI :
10.1007/BF02532837
Article number:
0
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
30524
Last updated date:
21/08/2022 07:45
Creation date:
17/04/2018 00:55
Scientific Publication
Site of bile acid absorption in the rat
11
Sklan, D., Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel
Budowski, P., Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel
Hurwitz, S., Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel
Site of bile acid absorption in the rat
Bile acid absorption was measured in the small intestine of the rat using91Y as a nonabsorbed reference substance. Some 50% of the secreted bile acids were absorbed in the proximal half of the small intestine. In situ incubations of ligated intestinal segments into which tauro(14C-carbonyl)cholic acid was introduced confirmed the considerable uptake of bile acids in the jejunum. The in situ experiments indicated that serosal transport is the limiting stage of bile acid absorption in the jejunum but not in the ileum. Increasing bile acid concentrations in the in situ experiments did not affect the percentage disappearance of dose from the jejunum but reduced the percentage mucosal uptake in the ileum. It is concluded that, in the rat, the proximal small intestine is as important in the absorption of bile acids as the distal small intestine. © 1976 American Oil Chemists' Society.
Scientific Publication
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