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פותח על ידי קלירמאש פתרונות בע"מ -
Metabolomics, genomics, proteomics, and the identification of enzymes and their substrates and products
Year:
2005
Source of publication :
Current Opinion in Plant Biology
Authors :
פרידמן, איל
;
.
Volume :
8
Co-Authors:
Fridman, E., Dept. Molec., Cell. Devmtl. Biol., University of Michigan, Ann Arbor, MI 48109-1048, United States
Pichersky, E., Dept. Molec., Cell. Devmtl. Biol., University of Michigan, Ann Arbor, MI 48109-1048, United States
Facilitators :
From page:
242
To page:
248
(
Total pages:
7
)
Abstract:
A large proportion of the genes in any plant genome encode enzymes of primary and specialized (secondary) metabolism. Not all plant primary metabolites, those that are found in all or most species, have been identified. Moreover, only a small portion of the estimated hundreds of thousand specialized metabolites, those found only in restricted lineages, have been studied in any species. The correlative analysis of extensive metabolic profiling and gene expression profiling has proven a powerful approach for the identification of candidate genes and enzymes, particularly those in secondary metabolism. The final characterization of substrates, enzymatic activities, and products requires biochemical analysis, which has been most successful when candidate proteins have homology to other enzymes of known function. The challenges are to identify new types of enzymes and to develop biochemical techniques that are suitable for large-scale analysis. © 2005 Elsevier Ltd. All rights reserved.
Note:
Related Files :
gene expression
Genetics
genomics
metabolism
Plants
proteomics
Review
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/j.pbi.2005.03.004
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
סקירה
;
.
Language:
אנגלית
Editors' remarks:
ID:
30930
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 00:58
Scientific Publication
Metabolomics, genomics, proteomics, and the identification of enzymes and their substrates and products
8
Fridman, E., Dept. Molec., Cell. Devmtl. Biol., University of Michigan, Ann Arbor, MI 48109-1048, United States
Pichersky, E., Dept. Molec., Cell. Devmtl. Biol., University of Michigan, Ann Arbor, MI 48109-1048, United States
Metabolomics, genomics, proteomics, and the identification of enzymes and their substrates and products
A large proportion of the genes in any plant genome encode enzymes of primary and specialized (secondary) metabolism. Not all plant primary metabolites, those that are found in all or most species, have been identified. Moreover, only a small portion of the estimated hundreds of thousand specialized metabolites, those found only in restricted lineages, have been studied in any species. The correlative analysis of extensive metabolic profiling and gene expression profiling has proven a powerful approach for the identification of candidate genes and enzymes, particularly those in secondary metabolism. The final characterization of substrates, enzymatic activities, and products requires biochemical analysis, which has been most successful when candidate proteins have homology to other enzymes of known function. The challenges are to identify new types of enzymes and to develop biochemical techniques that are suitable for large-scale analysis. © 2005 Elsevier Ltd. All rights reserved.
Scientific Publication
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