Cnaani, A., Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH, United States
Lee, B.-Y., Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH, United States
Ozouf-Costaz, C., Département Systématique et Evolution, Museum National d'Histoire Naturelle, Paris, France
Bonillo, C., Département Systématique et Evolution, Museum National d'Histoire Naturelle, Paris, France
Baroiller, J.F., CIRAD-Persyst, Aquaculture et Gestion des Ressources Aquatiques, Montpellier, France
D'Cotta, H., CIRAD-Persyst, Aquaculture et Gestion des Ressources Aquatiques, Montpellier, France
Kocher, T.D., Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH, United States, Department of Biology, University of Maryland, College Park, MD 20742, United States

Sox genes encode transcription factors that are involved in a variety of embryonic developmental pathways. Sox2 and Sox14 are located on the same chromosomal arm in several mammalian and bird species and on the basis of comparative maps were suggested as candidate genes for the major sex-determining locus on tilapia LG3. We have sequenced the sox2 and sox14 genes in four tilapia species and mapped them to different chromosomes, LG17 and LG23 respectively. Although excluded as being one of the major sex-determining genes so far mapped in tilapia, sox14 did fall within a QTL region for growth, stress response, embryonic mortality and a minor effect on sex determination. Copyright © 2007 S. Karger AG.