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פותח על ידי קלירמאש פתרונות בע"מ -
Mapping quantitative trait loci with DNA microsatellites in a commercial dairy cattle population
Year:
1994
Source of publication :
Animal Genetics
Authors :
ולר, יהודה
;
.
ינאי, אסף
;
.
ינאי, ענת
;
.
רון, מיכה
;
.
Volume :
25
Co-Authors:
Ron, M., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan, 50250, Israel
Band, M., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan, 50250, Israel
Yanai, A., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan, 50250, Israel
Weller, J.I., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan, 50250, Israel
Facilitators :
From page:
259
To page:
264
(
Total pages:
6
)
Abstract:
Individual loci affecting economically important traits can be located using genetic linkage between quantitative trait loci and genetic markers. In the ‘granddaughter’ experimental design, heterozygous grandsires and their sons are genotyped for the genetic marker, while the quantitative trait records of the granddaughters are used for statistical analysis. Ten DNA microsatellite markers were used to look for associations with quantitative trait loci affecting milk production traits in seven Israeli Holstein grandsire families. At least 60% more grandsires were heterozygous, and 40% fewer individuals were discarded because of unknown paternal allele origin, as compared with diallelic markers. The effects of paternal alleles for locus D21S4 on kg milk and protein were significant (P < 0.025). The allele substitution effects for sire 783 were 283 kg milk and 5.7 kg protein. For both traits, progeny of sire 783 that inherited allele ‘18’ had higher evaluations than progeny that inherited allele ‘21’. These results were verified by genotyping 151 of his daughters. Thus, the rate of genetic gain for protein production can be increased by selecting progeny of sire 783 carrying allele ‘18’ at this locus. © 1994 International Society for Animal Genetics
Note:
Related Files :
Animal
cattle
chromosome map
chromosome mapping
Female
genetic markers
Genetics
Male
עוד תגיות
תוכן קשור
More details
DOI :
10.1111/j.1365-2052.1994.tb00202.x
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
31624
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 01:04
You may also be interested in
Scientific Publication
Mapping quantitative trait loci with DNA microsatellites in a commercial dairy cattle population
25
Ron, M., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan, 50250, Israel
Band, M., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan, 50250, Israel
Yanai, A., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan, 50250, Israel
Weller, J.I., Institute of Animal Sciences, ARO, Volcani Center, Bet Dagan, 50250, Israel
Mapping quantitative trait loci with DNA microsatellites in a commercial dairy cattle population
Individual loci affecting economically important traits can be located using genetic linkage between quantitative trait loci and genetic markers. In the ‘granddaughter’ experimental design, heterozygous grandsires and their sons are genotyped for the genetic marker, while the quantitative trait records of the granddaughters are used for statistical analysis. Ten DNA microsatellite markers were used to look for associations with quantitative trait loci affecting milk production traits in seven Israeli Holstein grandsire families. At least 60% more grandsires were heterozygous, and 40% fewer individuals were discarded because of unknown paternal allele origin, as compared with diallelic markers. The effects of paternal alleles for locus D21S4 on kg milk and protein were significant (P < 0.025). The allele substitution effects for sire 783 were 283 kg milk and 5.7 kg protein. For both traits, progeny of sire 783 that inherited allele ‘18’ had higher evaluations than progeny that inherited allele ‘21’. These results were verified by genotyping 151 of his daughters. Thus, the rate of genetic gain for protein production can be increased by selecting progeny of sire 783 carrying allele ‘18’ at this locus. © 1994 International Society for Animal Genetics
Scientific Publication
You may also be interested in