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פותח על ידי קלירמאש פתרונות בע"מ -
IME1, a positive regulator gene of meiosis in S. cerevisiae
Year:
1988
Source of publication :
Cell
Authors :
גרנות, דוד
;
.
Volume :
52
Co-Authors:
Kassir, Y., Department of Genetics The Hebrew University Jerusalem, 91904, Israel
Granot, D., Department of Genetics The Hebrew University Jerusalem, 91904, Israel
Simchen, G., Department of Genetics The Hebrew University Jerusalem, 91904, Israel
Facilitators :
From page:
853
To page:
862
(
Total pages:
10
)
Abstract:
IMEI (inducer of MEiosis) was cloned due to its high copy number effect: it enabled MAT insufficient strains to undergo meiosis. Disruption of IMEI results in a recessive Spo- phenotype. Diploids homozygous for the two mutations ime1-0, rmel-1 are also meios deficient. We conclude that IME1 is a positive regultor of meiosis that normally is repressed by RME1. RME is repressed by a complex of MATal and MATα2 gene products. IME1 is also regulated by the environment: no transcripts could be detected in glucose growing cells, in contrast to acetate growing cell. Starvation for nitrogen further induced (6- to 8-fold) transcription of IME1, but, as expected, the induction was found only in MATa/MATα or rmel-l/rme1-1 diploids. Furthermore, the IME1 multicopy plasmids promoted sporulation in rich media. © 1988.
Note:
Related Files :
Genes, Fungal
genetic markers
Genetics
Growth, Development and Aging
Plasmid
regulator gene
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/0092-8674(88)90427-8
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
31716
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 01:04
You may also be interested in
Scientific Publication
IME1, a positive regulator gene of meiosis in S. cerevisiae
52
Kassir, Y., Department of Genetics The Hebrew University Jerusalem, 91904, Israel
Granot, D., Department of Genetics The Hebrew University Jerusalem, 91904, Israel
Simchen, G., Department of Genetics The Hebrew University Jerusalem, 91904, Israel
IME1, a positive regulator gene of meiosis in S. cerevisiae
IMEI (inducer of MEiosis) was cloned due to its high copy number effect: it enabled MAT insufficient strains to undergo meiosis. Disruption of IMEI results in a recessive Spo- phenotype. Diploids homozygous for the two mutations ime1-0, rmel-1 are also meios deficient. We conclude that IME1 is a positive regultor of meiosis that normally is repressed by RME1. RME is repressed by a complex of MATal and MATα2 gene products. IME1 is also regulated by the environment: no transcripts could be detected in glucose growing cells, in contrast to acetate growing cell. Starvation for nitrogen further induced (6- to 8-fold) transcription of IME1, but, as expected, the induction was found only in MATa/MATα or rmel-l/rme1-1 diploids. Furthermore, the IME1 multicopy plasmids promoted sporulation in rich media. © 1988.
Scientific Publication
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