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פותח על ידי קלירמאש פתרונות בע"מ -
Enhanced antibody response in cattle against Leptospira hardjo by intradermal vaccination
Year:
1997
Source of publication :
Vaccine
Authors :
מועלם, עוזי
;
.
Volume :
15
Co-Authors:
Samina, I., State Laboratory for Vaccine Control, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Brenner, J., Laboratory of Immunology, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Moalem, U., Volcani Exp. Agriculture Center, 50250 Bet Dagan, Israel
Berenstein, M., Laboratory of Bacteriology, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Cohen, A., Laboratory of Bacteriology, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Peleg, B.A., State Laboratory for Vaccine Control, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Facilitators :
From page:
1434
To page:
1436
(
Total pages:
3
)
Abstract:
A commercial killed Leptospira hardjo vaccine (with adjuvant) and non- adjuvanted preparation of the same vaccine were used in comparison of the effectiveness of the intradermal (i.d.) and subcutaneous (s.c.) routes for these vaccines. The tests were conducted in 50 females aged 6-14 months. After the first vaccination, both types of vaccine elicited a very poor antibody response by both routes of vaccination. However, after booster vaccination, the commercial vaccine (with adjuvant) elicited a remarkable immune response which was twice as high by i.d. compared with s.c. vaccination. No local or general adverse reactions were observed after i.d. vaccination with the adjuvanted commercial vaccine (potassium aluminium sulphate).
Note:
Related Files :
animal model
Animals
cattle
Female
intradermal drug administration
leptospirosis vaccine
unclassified drug
Vaccination
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/S0264-410X(97)00046-7
Article number:
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
32063
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 01:07
You may also be interested in
Scientific Publication
Enhanced antibody response in cattle against Leptospira hardjo by intradermal vaccination
15
Samina, I., State Laboratory for Vaccine Control, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Brenner, J., Laboratory of Immunology, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Moalem, U., Volcani Exp. Agriculture Center, 50250 Bet Dagan, Israel
Berenstein, M., Laboratory of Bacteriology, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Cohen, A., Laboratory of Bacteriology, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Peleg, B.A., State Laboratory for Vaccine Control, Kimou Veterinary Institute, 50250 Bet Dagan, Israel
Enhanced antibody response in cattle against Leptospira hardjo by intradermal vaccination
A commercial killed Leptospira hardjo vaccine (with adjuvant) and non- adjuvanted preparation of the same vaccine were used in comparison of the effectiveness of the intradermal (i.d.) and subcutaneous (s.c.) routes for these vaccines. The tests were conducted in 50 females aged 6-14 months. After the first vaccination, both types of vaccine elicited a very poor antibody response by both routes of vaccination. However, after booster vaccination, the commercial vaccine (with adjuvant) elicited a remarkable immune response which was twice as high by i.d. compared with s.c. vaccination. No local or general adverse reactions were observed after i.d. vaccination with the adjuvanted commercial vaccine (potassium aluminium sulphate).
Scientific Publication
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