אסיף מאגר המחקר החקלאי

DNA-binding proteins in the nuclei of herpes simplex virus-infected, arginine-deprived, BSC-1 cells

Year:

1980

Source of publication :

Authors :

Volume :

50

Co-Authors:

Becker, Y., Dept. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Chejanovsky, N., Dept. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Fridlender, B., Dept. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel

Facilitators :

Link :

Abstract:

Nine proteins accumulate in nuclei of arginine-deprived herpes simplex virus infected cells. Of these, eight were found to bind to double-stranded DNA-cellulose and to elute wtih 0.3 and 0.6 M-KCl, while one of 160 000 mol. wt. had no affinity for the DNA. Five of the DNA-binding proteins were identified as virus enzymes: two were DNA polymerases, two were alkaline DNases and one was the thymidine kinase.

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