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פותח על ידי קלירמאש פתרונות בע"מ -
Using the baculovirus/insect cell system to study apoptosis -2016
Year:
2016
Source of publication :
Methods in Molecular Biology
Authors :
צ'חנובסקי, נור
;
.
Volume :
1350
Co-Authors:
Facilitators :
From page:
477
To page:
489
(
Total pages:
13
)
Abstract:
Apoptosis is a physiological program of cell suicide conserved in invertebrates and vertebrates. Apoptosis is crucial to the normal development of organisms and in tissue homeostasis by promoting elimination of unwanted cells, including damaged or virus-infected cells. Due to the importance of programmed cell death for the survival of the organism, a tight regulation is exerted at various activation levels of the celldeath machinery. The utilization of the baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) to identify genes that inhibit the apoptotic process will be described using a transfection-based approach, illustrated by identification of the p49 gene. © Springer Science+Business Media, LLC 2016.
Note:
Related Files :
animal cell
apoptosis
Baculoviridae
dna transfection
gene expression
עוד תגיות
תוכן קשור
More details
DOI :
10.1007/978-1-4939-3043-2_25
Article number:
0
Affiliations:
Database:
סקופוס
Publication Type:
פרק מתוך ספר
;
.
Language:
אנגלית
Editors' remarks:
ID:
32378
Last updated date:
02/03/2022 17:27
Creation date:
17/04/2018 01:09
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Scientific Publication
Using the baculovirus/insect cell system to study apoptosis -2016
1350
Using the baculovirus/insect cell system to study apoptosis
Apoptosis is a physiological program of cell suicide conserved in invertebrates and vertebrates. Apoptosis is crucial to the normal development of organisms and in tissue homeostasis by promoting elimination of unwanted cells, including damaged or virus-infected cells. Due to the importance of programmed cell death for the survival of the organism, a tight regulation is exerted at various activation levels of the celldeath machinery. The utilization of the baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) to identify genes that inhibit the apoptotic process will be described using a transfection-based approach, illustrated by identification of the p49 gene. © Springer Science+Business Media, LLC 2016.
Scientific Publication
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