Co-Authors:
Ben-Hur, E., Nuclear Research Center-Negev, P.O. Box 9001, Beer-Sheva, 84100, Israel
Kol, R., ARO, The Volcani Center, Bet-Dagan, 50250, Israel
Marko, R., Nuclear Research Center-Negev, P.O. Box 9001, Beer-Sheva, 84100, Israel
Riklis, E., Nuclear Research Center-Negev, P.O. Box 9001, Beer-Sheva, 84100, Israel
Rosenthal, I., Nuclear Research Center-Negev, P.O. Box 9001, Beer-Sheva, 84100, Israel
Abstract:
The response of Chinese hamster cells and human lymphocytes to the combined action of photosensitization by chloroaluminium phthalocyanine tetrasulfonate and gamma-radiation was studied using colony-forming ability and [3H]thymidine incorporation following mitogenic stimulation respectively, as endpoints. The action of both treatments was usually additive regardless of the sequence of application. However, in human lymphocytes irradiated at low temperature, the photosensitization interacted synergistically with the sub-sequent ionizing radiation; in this experiment the initial photosensitization reduced the yield of micronuclei produced by gamma-radiation. © 1988 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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