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פותח על ידי קלירמאש פתרונות בע"מ -
Antiinflammatory Potential of Medicinal Plants: A Source for Therapeutic Secondary Metabolites
Year:
2018
Source of publication :
Advances in Agronomy
Authors :
ברנשטיין, נירית
;
.
פרידלנדר, מרסלו
;
.
קולטאי, חננית
;
.
Volume :
150
Co-Authors:

Akram, M.; Daniyal, M.; Gorelick, J.

Facilitators :
From page:
131
To page:
183
(
Total pages:
53
)
Abstract:

Plants containing natural products have been used worldwide in traditional medicine since antiquity and are a source of potential and powerful drugs. The potential of higher plants as a source for new drugs is still largely unexplored, and among the estimated 250,000–500,000 plant species, only a small fraction has been submitted to biological or pharmacological screening. Medicinal plants and their isolated compounds are utilized worldwide in traditional medicine for the treatment of various inflammatory conditions, and the therapeutic potential of traditionally used plants and their constituents is currently a target of research in the pursuit of novel antiinflammatory drugs. Inflammation is the normal reaction of animal living tissue to all forms of injury. It is a dynamic and complex tissue reaction provoked by cellular injury, which involves a cascade of biochemical events. Although inflammation is a protective measure taken by the organism to eliminate the injurious stimuli, uncontrolled inflammation can lead to damage. For this reason, inflammation is closely regulated by the body or with the aid of administrated antiinflammatory compounds. The search for alternative substances capable of interfering with the inflammatory process has become a significant issue in scientific research, especially with reference to the search for natural substances and the reduction of negative side effects of conventional medications. Although dozens of plant species were reported in ethnomedicine for the treatment of inflammation, only a fraction of these were confirmed in antiinflammatory studies. This review evaluates the current state of knowledge concerning promising antiinflammatory activity of herbal plants and plant substances that have been tested in inflammatory models using modern scientific systems. © 2018 Elsevier Inc.

Note:
Related Files :
Antiinflammatory
Inflammation
medicinal plants
medicinal plants
metabolites
Natural products plants
עוד תגיות
תוכן קשור
More details
DOI :
https://doi.org/10.1016/bs.agron.2018.02.003
Article number:
0
Affiliations:

Institute of Soil Water and Environmental Sciences, Volcani Center, Rishon LeZion, Israel; Directorate of Medical Sciences, Government College University, Faisalabad, Pakistan; School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China; College of Biology, Hunan University, Changsha, China; Institute of Plant Sciences, Volcani Center, Rishon LeZion, Israel; Judea Regional Research and Development Center, Kiryat Arba, Israel

Database:
סקופוס
Publication Type:
פרק מתוך ספר
;
.
Language:
אנגלית
Editors' remarks:
ID:
36091
Last updated date:
02/03/2022 17:27
Creation date:
01/08/2018 09:58
Scientific Publication
Antiinflammatory Potential of Medicinal Plants: A Source for Therapeutic Secondary Metabolites
150

Akram, M.; Daniyal, M.; Gorelick, J.

Antiinflammatory Potential of Medicinal Plants: A Source for Therapeutic Secondary Metabolites

Plants containing natural products have been used worldwide in traditional medicine since antiquity and are a source of potential and powerful drugs. The potential of higher plants as a source for new drugs is still largely unexplored, and among the estimated 250,000–500,000 plant species, only a small fraction has been submitted to biological or pharmacological screening. Medicinal plants and their isolated compounds are utilized worldwide in traditional medicine for the treatment of various inflammatory conditions, and the therapeutic potential of traditionally used plants and their constituents is currently a target of research in the pursuit of novel antiinflammatory drugs. Inflammation is the normal reaction of animal living tissue to all forms of injury. It is a dynamic and complex tissue reaction provoked by cellular injury, which involves a cascade of biochemical events. Although inflammation is a protective measure taken by the organism to eliminate the injurious stimuli, uncontrolled inflammation can lead to damage. For this reason, inflammation is closely regulated by the body or with the aid of administrated antiinflammatory compounds. The search for alternative substances capable of interfering with the inflammatory process has become a significant issue in scientific research, especially with reference to the search for natural substances and the reduction of negative side effects of conventional medications. Although dozens of plant species were reported in ethnomedicine for the treatment of inflammation, only a fraction of these were confirmed in antiinflammatory studies. This review evaluates the current state of knowledge concerning promising antiinflammatory activity of herbal plants and plant substances that have been tested in inflammatory models using modern scientific systems. © 2018 Elsevier Inc.

Scientific Publication
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