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פותח על ידי קלירמאש פתרונות בע"מ -
Gene therapy in a sheep model of CNGA3 achromatopsia
Year:
2014
Authors :
גוטויין, אלישע
;
.
רוזוב, אלכסנדר
;
.
Volume :
55
Co-Authors:
Eyal Banin,Ayala Ejzenberg,Lina Zelinger, Edward Averbukh - Ophthalmology, Hadassah-Hebrew Univ Med Ctr, Jerusalem, Israel
Raaya Ezra-Elia, Ron Ofri  -Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
William W Hauswirth - Ophthalmology, University of Florida, Gainsville, FL
 
 
 
Facilitators :
From page:
0
To page:
0
(
Total pages:
1
)
Abstract:

PurposeMutations in the CNGA3 gene cause achromatopsia in humans. We identified a spontaneously-arising sheep model for this disease (Shamir et. al., Vet J. 185(2):130-7, 2010; Reicher et al., Genomics 95:101-4, 2010), and used this model to test the efficacy and safety of viral vector-mediated gene therapy.

Note:
Related Files :
gene therapy
gene transfer
retinal degenerations: hereditary
עוד תגיות
תוכן קשור
More details
DOI :
Article number:
0
Affiliations:
Database:
גוגל סקולר
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
43825
Last updated date:
02/03/2022 17:27
Creation date:
09/09/2019 12:33
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Scientific Publication
Gene therapy in a sheep model of CNGA3 achromatopsia
55
Eyal Banin,Ayala Ejzenberg,Lina Zelinger, Edward Averbukh - Ophthalmology, Hadassah-Hebrew Univ Med Ctr, Jerusalem, Israel
Raaya Ezra-Elia, Ron Ofri  -Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
William W Hauswirth - Ophthalmology, University of Florida, Gainsville, FL
 
 
 
Gene therapy in a sheep model of CNGA3 achromatopsia .

PurposeMutations in the CNGA3 gene cause achromatopsia in humans. We identified a spontaneously-arising sheep model for this disease (Shamir et. al., Vet J. 185(2):130-7, 2010; Reicher et al., Genomics 95:101-4, 2010), and used this model to test the efficacy and safety of viral vector-mediated gene therapy.

Scientific Publication
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