תפריט נגישות
ניגודיות עדינהניגודיות גבוהה
מונוכרום
הדגשת קישורים
חסימת אנימציה
פונט קריא
סגור
איפוס הגדרות נגישות
להורדת מודול נגישות חינם תפריט נגישותניגודיות עדינהניגודיות גבוההמונוכרוםהדגשת קישוריםחסימת אנימציהפונט קריאסגוראיפוס הגדרות נגישותלהורדת מודול נגישות חינםDorin Harpaz _ Institute of Biochemistry, Food science & Nutrition, Faculty of Agriculture, Food & Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel; Department of Postharvest Science, Institute of Postharvest and Food Sciences, The Volcani Center, Agricultural Research Organization, Rishon LeZion 7505101, Israel.
Robert S Marks _ Avram & Stella Goldstein-Goren Department of Biotechnology Engineering, Faculty of Engineering Science, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel; The Ilse Katz Center for Meso & Nanoscale Science & Technology, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Ariel Kushmaro _ Avram & Stella Goldstein-Goren Department of Biotechnology Engineering, Faculty of Engineering Science, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel; The Ilse Katz Center for Meso & Nanoscale Science & Technology, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Evgeni Eltzov _ Department of Postharvest Science, Institute of Postharvest and Food Sciences, The Volcani Center, Agricultural Research Organization, Rishon LeZion 7505101, Israel.
Aim: The mechanisms behind antibiotic resistance by bacteria are important to create alternative molecules. Objective: This study focuses on the impact of environmental pollutants on bacterial resistance to antibiotics. Materials & methods: The effect of various environmental pollutants on noninherited bacterial resistance to antibiotics was examined. Results: The tolerance to the polymyxin-B antibiotic was shown to be conferred to Escherichia coli, by pretreatment with subinhibitory concentrations of environmental toxicants. The cell survival to a sublethal dosage of antibiotics was tested. Exposure to low concentrations of toxic compounds (500 ppb copper, 2% [v/v] ethanol or 0.5 μg/ml trimethoprim) stimulated the bacterial heat shock systems and led to increased tolerance to polymyxin B. Conclusion: Environmental pollutants induce a temporary bacterial noninheritable resistance to antibiotic.
Dorin Harpaz _ Institute of Biochemistry, Food science & Nutrition, Faculty of Agriculture, Food & Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel; Department of Postharvest Science, Institute of Postharvest and Food Sciences, The Volcani Center, Agricultural Research Organization, Rishon LeZion 7505101, Israel.
Robert S Marks _ Avram & Stella Goldstein-Goren Department of Biotechnology Engineering, Faculty of Engineering Science, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel; The Ilse Katz Center for Meso & Nanoscale Science & Technology, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Ariel Kushmaro _ Avram & Stella Goldstein-Goren Department of Biotechnology Engineering, Faculty of Engineering Science, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel; The Ilse Katz Center for Meso & Nanoscale Science & Technology, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Evgeni Eltzov _ Department of Postharvest Science, Institute of Postharvest and Food Sciences, The Volcani Center, Agricultural Research Organization, Rishon LeZion 7505101, Israel.
Aim: The mechanisms behind antibiotic resistance by bacteria are important to create alternative molecules. Objective: This study focuses on the impact of environmental pollutants on bacterial resistance to antibiotics. Materials & methods: The effect of various environmental pollutants on noninherited bacterial resistance to antibiotics was examined. Results: The tolerance to the polymyxin-B antibiotic was shown to be conferred to Escherichia coli, by pretreatment with subinhibitory concentrations of environmental toxicants. The cell survival to a sublethal dosage of antibiotics was tested. Exposure to low concentrations of toxic compounds (500 ppb copper, 2% [v/v] ethanol or 0.5 μg/ml trimethoprim) stimulated the bacterial heat shock systems and led to increased tolerance to polymyxin B. Conclusion: Environmental pollutants induce a temporary bacterial noninheritable resistance to antibiotic.
