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פותח על ידי קלירמאש פתרונות בע"מ -
A half century of fish gonadotropin-releasing hormones: Breaking paradigms
Year:
2021
Source of publication :
Journal of Neuroendocrinology
Authors :
גולן, מתן
;
.
Volume :
Co-Authors:

Yonathan Zohar,
Nilli Zmora,
Vance L. Trudeau,
José A. Muñoz-Cueto,
Matan Golan

Facilitators :
From page:
0
To page:
0
(
Total pages:
1
)
Abstract:

The field of fish gonadotropin-releasing hormones (GnRHs) is also celebrating its 50th anniversary this year. This review provides a chronological history of fish GnRH biology over the past five decades. It demonstrates how discoveries in fish regarding GnRH and GnRH receptor multiplicity, dynamic interactions between GnRH neurons, and additional neuroendocrine factors acting alongside GnRH, amongst others, have driven a paradigm shift in our understanding of GnRH systems and functions in vertebrates, including mammals. The role of technological innovations in enabling scientific discoveries is portrayed, as well as how fundamental research in fish GnRH led to translational outcomes in aquaculture. The interchange between fish and mammalian GnRH research is discussed, as is the value and utility of using fish models for advancing GnRH biology. Current challenges and future perspectives are presented, with the hope of expanding the dialogue and collaborations within the neuroendocrinology scientific community at large, capitalizing on diversifying model animals and the use of comparative strategies.

Note:
Related Files :
aquaculture
fish gonadotropin-releasing hormones (GnRHs)
עוד תגיות
תוכן קשור
More details
DOI :
10.1111/jne.13069
Article number:
0
Affiliations:
Database:
סקופוס
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
57381
Last updated date:
02/03/2022 17:27
Creation date:
28/12/2021 21:49
Scientific Publication
A half century of fish gonadotropin-releasing hormones: Breaking paradigms

Yonathan Zohar,
Nilli Zmora,
Vance L. Trudeau,
José A. Muñoz-Cueto,
Matan Golan

A half century of fish gonadotropin-releasing hormones: Breaking paradigms

The field of fish gonadotropin-releasing hormones (GnRHs) is also celebrating its 50th anniversary this year. This review provides a chronological history of fish GnRH biology over the past five decades. It demonstrates how discoveries in fish regarding GnRH and GnRH receptor multiplicity, dynamic interactions between GnRH neurons, and additional neuroendocrine factors acting alongside GnRH, amongst others, have driven a paradigm shift in our understanding of GnRH systems and functions in vertebrates, including mammals. The role of technological innovations in enabling scientific discoveries is portrayed, as well as how fundamental research in fish GnRH led to translational outcomes in aquaculture. The interchange between fish and mammalian GnRH research is discussed, as is the value and utility of using fish models for advancing GnRH biology. Current challenges and future perspectives are presented, with the hope of expanding the dialogue and collaborations within the neuroendocrinology scientific community at large, capitalizing on diversifying model animals and the use of comparative strategies.

Scientific Publication
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