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אסיף מאגר המחקר החקלאי
פותח על ידי קלירמאש פתרונות בע"מ -
Direct effects of phenolic compounds on the mammary gland: In vivo and ex vivo evidence
Year:
2021
Source of publication :
Food Chemistry
Authors :
דויטש, טובה
;
.
לנדאו, יאן
;
.
מוקלדה, חוסיין
;
.
Volume :
Co-Authors:

Oren Hadaya 
Serge Yan Landau
Hussein Muklada
Tova Deutch-Traubmann
Tzach Glasser
Rawan Bransi-Nicola
Hassan Azaizeh
Safaa Awwad
Fares Halahlih
Yoav Shalev
Nurit Argov-Argaman

Facilitators :
From page:
0
To page:
0
(
Total pages:
1
)
Abstract:

We assessed the potential of Pistacia lentiscus (lentisk) phenolic compounds to enhance production of milk composition in lactating goats and caprine primary mammary epithelial cells (MEC). Damascus goats were given a lentisk infusion (LI) or fresh water (FW) to drink, in a crossover design. Milk from LI vs. FW goats was 0.43% richer in fat and 30% in omega 3 fatty acids. Lentisk infusion enhanced antioxidant capacity of plasma and milk by 37% and 30% respectively, and induced transcriptional activation of antioxidant genes. To assess the direct effect of polyphenols on milk quality in terms of composition and antioxidant capacity, we used plasma collected from goats fed hay (HP) or browsed on phenolic compounds-rich pasture (primarily lentisk; PP) as a conditioning medium for primary culture of MEC. PP increased 2-fold cellular triglyceride content and 2.4-fold intracellular casein, and increased ATP production and non-mitochondrial oxygen consumption. Taken together, the results imply that lentisk phenolic compounds affect blood, MEC and milk oxidative status, which increase fat production by the mammary gland.

Note:
Related Files :
Dairy goat
Lentisk
Mammary epithelial cell
oxidative stress
phenolic compound
עוד תגיות
תוכן קשור
More details
DOI :
10.1016/j.fochms.2021.100034
Article number:
0
Affiliations:
Database:
PubMed
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
59515
Last updated date:
15/06/2022 17:06
Creation date:
15/06/2022 17:05
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Scientific Publication
Direct effects of phenolic compounds on the mammary gland: In vivo and ex vivo evidence

Oren Hadaya 
Serge Yan Landau
Hussein Muklada
Tova Deutch-Traubmann
Tzach Glasser
Rawan Bransi-Nicola
Hassan Azaizeh
Safaa Awwad
Fares Halahlih
Yoav Shalev
Nurit Argov-Argaman

Direct effects of phenolic compounds on the mammary gland: In vivo and ex vivo evidence .

We assessed the potential of Pistacia lentiscus (lentisk) phenolic compounds to enhance production of milk composition in lactating goats and caprine primary mammary epithelial cells (MEC). Damascus goats were given a lentisk infusion (LI) or fresh water (FW) to drink, in a crossover design. Milk from LI vs. FW goats was 0.43% richer in fat and 30% in omega 3 fatty acids. Lentisk infusion enhanced antioxidant capacity of plasma and milk by 37% and 30% respectively, and induced transcriptional activation of antioxidant genes. To assess the direct effect of polyphenols on milk quality in terms of composition and antioxidant capacity, we used plasma collected from goats fed hay (HP) or browsed on phenolic compounds-rich pasture (primarily lentisk; PP) as a conditioning medium for primary culture of MEC. PP increased 2-fold cellular triglyceride content and 2.4-fold intracellular casein, and increased ATP production and non-mitochondrial oxygen consumption. Taken together, the results imply that lentisk phenolic compounds affect blood, MEC and milk oxidative status, which increase fat production by the mammary gland.

Scientific Publication
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