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פותח על ידי קלירמאש פתרונות בע"מ -
Reactivity of Vitamin E as an Antioxidant in Red Meat and the Stomach Medium
Year:
2022
Authors :
קנר, יוסף
;
.
Volume :
Co-Authors:

Boris Rabkin
Oren Tirosh
Joseph Kanner 

Facilitators :
From page:
0
To page:
0
(
Total pages:
1
)
Abstract:

The stomach is a bioreactor and an important intersection of biochemical reactions that affect human health. Lipid peroxidation of meat in the stomach medium generates malondialdehyde (MDA), which is absorbed from the gut into human plasma and modifies low-density lipoprotein (LDL) to MDA-LDL. We found in the stomach medium (pH 3.0) a high antioxidant activity of vitamin E against meat lipid peroxidation, almost 35-fold higher than at pH 6.3. In the stomach medium, the antioxidant activity of vitamin E on meat lipid peroxidation was 20-fold higher than that of catechin. Vitamin E, at pH 3.0, acts synergistically with metmyoglobin (MbFe+3), as a peroxidase/antioxidant couple. The synergistic effect of MbFe+3/vitamin E was almost 150-fold higher than the antioxidant effect achieved by MbFe+3/catechin. The meat antioxidant activity was maintained continuously by addition of a low concentration of vitamin E, catechin, and vitamin C, preventing the propagation of lipid oxidation, reactive aldehyde generation, and the loss of vitamin E.

Note:
Related Files :
antioxidants
lipid peroxidation
oxidative stress
red meat
stomach medium
Vitamin E
עוד תגיות
תוכן קשור
More details
DOI :
10.1021/acs.jafc.2c03674
Article number:
0
Affiliations:
Database:
PubMed
Publication Type:
מאמר
;
.
Language:
אנגלית
Editors' remarks:
ID:
62333
Last updated date:
03/10/2022 18:50
Creation date:
03/10/2022 18:49
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Scientific Publication
Reactivity of Vitamin E as an Antioxidant in Red Meat and the Stomach Medium

Boris Rabkin
Oren Tirosh
Joseph Kanner 

Reactivity of Vitamin E as an Antioxidant in Red Meat and the Stomach Medium

The stomach is a bioreactor and an important intersection of biochemical reactions that affect human health. Lipid peroxidation of meat in the stomach medium generates malondialdehyde (MDA), which is absorbed from the gut into human plasma and modifies low-density lipoprotein (LDL) to MDA-LDL. We found in the stomach medium (pH 3.0) a high antioxidant activity of vitamin E against meat lipid peroxidation, almost 35-fold higher than at pH 6.3. In the stomach medium, the antioxidant activity of vitamin E on meat lipid peroxidation was 20-fold higher than that of catechin. Vitamin E, at pH 3.0, acts synergistically with metmyoglobin (MbFe+3), as a peroxidase/antioxidant couple. The synergistic effect of MbFe+3/vitamin E was almost 150-fold higher than the antioxidant effect achieved by MbFe+3/catechin. The meat antioxidant activity was maintained continuously by addition of a low concentration of vitamin E, catechin, and vitamin C, preventing the propagation of lipid oxidation, reactive aldehyde generation, and the loss of vitamin E.

Scientific Publication
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