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The effects of soy flour and N-nitrosobis (2-oxopropyl) amine on the pancreas of the hamster
Year:
1985
Source of publication :
Drug-Nutrient Interactions
Authors :
Hasdai, Aharon
;
.
Volume :
3
Co-Authors:
Hasdai, A., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States
Liener, I.E., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States
Facilitators :
From page:
173
To page:
179
(
Total pages:
7
)
Abstract:
Syrian golden hamsters fed diets of raw or heated soy flour for 16 months had an incidence (4%) of pancreatic neoplasms in both groups. Animals injected with N-nitrosobis (2-oxopropyl) amine (BOP) and fed heated soy flour for 15 months developed a high incidence (88%) of microscopic benign and malignant neoplasms, primarily of ductal origin. This was in marked contrast to a similar group of BOP-induced animals which had been fed raw soy flour and in which the incidence of pancreatic neoplasms was less than 10%.
Note:
Related Files :
Animal
animal cell
bis(2 oxopropyl)nitrosamine
Hamsters
intoxication
Male
Nitrosamines
Pancreas
pancreas tumor
soybean
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More details
DOI :
Article number:
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
20215
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:34
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Scientific Publication
The effects of soy flour and N-nitrosobis (2-oxopropyl) amine on the pancreas of the hamster
3
Hasdai, A., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States
Liener, I.E., Department of Biochemistry, University of Minnesota, St. Paul, MN 55108, United States
The effects of soy flour and N-nitrosobis (2-oxopropyl) amine on the pancreas of the hamster
Syrian golden hamsters fed diets of raw or heated soy flour for 16 months had an incidence (4%) of pancreatic neoplasms in both groups. Animals injected with N-nitrosobis (2-oxopropyl) amine (BOP) and fed heated soy flour for 15 months developed a high incidence (88%) of microscopic benign and malignant neoplasms, primarily of ductal origin. This was in marked contrast to a similar group of BOP-induced animals which had been fed raw soy flour and in which the incidence of pancreatic neoplasms was less than 10%.
Scientific Publication
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