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Effect of ethylene dibromide and carbon tetrachloride on lipid peroxidation in rat and chick liver
Year:
1972
Authors :
Nachtomi, Edna
;
.
Volume :
17
Co-Authors:
Nachtomi, E., Division of Animal Nutrition, Agricultural Research Organization, The Volcani Center, Rehovoi, Israel
Facilitators :
From page:
171
To page:
175
(
Total pages:
5
)
Abstract:
Lipid peroxidation in vitro of carbon tetrachloride (CCl4) and ethylene dibromide (EDB) in microsomal supernatant fraction (MSF) of chick and rat livers was evaluated by measuring the malonaldehyde concentration after incubation with thiobarbituric acid. The additive peroxidation effect of CCl4 in rat liver NADPH-induced system, was confirmed. The addition of EDB to the system had no effect on lipid peroxidation. The addition of NADPH to MSF of chick liver caused a marked increase in peroxidation. Both CCl4 and EDB inhibited peroxidation in the above system. The different response of the two species to the CCl4 hepatotoxicity is discussed. © 1972.
Note:
Related Files :
Animal
biosynthesis
Chickens
drug effect
Lipids
Male
metabolism
Microsomes, Liver
Show More
Related Content
More details
DOI :
10.1016/0014-4800(72)90066-4
Article number:
Affiliations:
Database:
Scopus
Publication Type:
article
;
.
Language:
English
Editors' remarks:
ID:
21270
Last updated date:
02/03/2022 17:27
Creation date:
16/04/2018 23:42
Scientific Publication
Effect of ethylene dibromide and carbon tetrachloride on lipid peroxidation in rat and chick liver
17
Nachtomi, E., Division of Animal Nutrition, Agricultural Research Organization, The Volcani Center, Rehovoi, Israel
Effect of ethylene dibromide and carbon tetrachloride on lipid peroxidation in rat and chick liver
Lipid peroxidation in vitro of carbon tetrachloride (CCl4) and ethylene dibromide (EDB) in microsomal supernatant fraction (MSF) of chick and rat livers was evaluated by measuring the malonaldehyde concentration after incubation with thiobarbituric acid. The additive peroxidation effect of CCl4 in rat liver NADPH-induced system, was confirmed. The addition of EDB to the system had no effect on lipid peroxidation. The addition of NADPH to MSF of chick liver caused a marked increase in peroxidation. Both CCl4 and EDB inhibited peroxidation in the above system. The different response of the two species to the CCl4 hepatotoxicity is discussed. © 1972.
Scientific Publication
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