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Fridlender, B., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Chejanovsky, N., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Becker, Y., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
The phosphonoacetic acid (PAA)-susceptible deoxyribonucleic acid (DNA) polymerase of herpes simplex virus type 1 was partially purified and isolated in sucrose gradients and on double-strand DNA cellulose columns. The DNA polymerase isolated from cells infected with the PAA-resistant mutant had the same molecular weight as the wild- type enzyme (140,000 to 149,000) but was consistently more resistant to PAA.
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Deoxyribonucleic acid polymerase of wild type and phosphonoacetic acid resistant mutant of herpes simplex virus
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Fridlender, B., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Chejanovsky, N., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Becker, Y., Lab. Molec. Virol., Hebrew Univ. Hadassah Med. Sch., Jerusalem, Israel
Deoxyribonucleic acid polymerase of wild type and phosphonoacetic acid resistant mutant of herpes simplex virus
The phosphonoacetic acid (PAA)-susceptible deoxyribonucleic acid (DNA) polymerase of herpes simplex virus type 1 was partially purified and isolated in sucrose gradients and on double-strand DNA cellulose columns. The DNA polymerase isolated from cells infected with the PAA-resistant mutant had the same molecular weight as the wild- type enzyme (140,000 to 149,000) but was consistently more resistant to PAA.
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