22-trans-cholesta-5,22,24-trien-3β-OL - An intermediate in the conversion of stigmasterol to cholesterol in the tobacco hornworm, Manduca sexta (Johannson)

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22-trans-cholesta-5,22,24-trien-3β-OL - An intermediate in the conversion of stigmasterol to cholesterol in the tobacco hornworm, Manduca sexta (Johannson)

Year: 

1969

Source of publication :

Steroids

Authors :

Svoboda, James

.

Volume :

Co-Authors: 

Svoboda, J.A., Insect Physiology Laboratory, Agricultural Research Service, U. S. Department of Agriculture Beltsville, MD 20705, United States
Hutchins, R.F.N., Insect Physiology Laboratory, Agricultural Research Service, U. S. Department of Agriculture Beltsville, MD 20705, United States
Thompson, M.J., Insect Physiology Laboratory, Agricultural Research Service, U. S. Department of Agriculture Beltsville, MD 20705, United States
Robbins, W.E., Insect Physiology Laboratory, Agricultural Research Service, U. S. Department of Agriculture Beltsville, MD 20705, United States

From page: 

469

To page: 

476

(

Total pages: 

8

)

Link :

22-trans-cholesta-5,22,24-trien-3β-OL - An intermediate in the conversion of stigmasterol to cholesterol in the tobacco hornworm, Manduca sexta (Johannson)

Abstract: 

A new sterol, 22-trans-cholesta-5,22,24-trien-3β-ol, was isolated and identified as an intermediate in the conversion of stigmasterol to cholesterol in the tobacco hornworm. This intermediate, which is normally present in stigmasterol-fed insects, accumulates when the conversion of stigmasterol to cholesterol is inhibited by 20,25-diazacholesterol. Synthetic 22-trans-cholesta-5,22,24-trien-3β-ol supported normal growth and development and was converted to cholesterol by the tobacco hornworm. © 1968 Holden-Day, Inc.