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Journal of Dairy Science
Green, M., Nuclear Research Center-Negev, P.O.B. 9001, Beer Sheva, Israel
Ben-Hur, E., Nuclear Research Center-Negev, P.O.B. 9001, Beer Sheva, Israel
Riklis, E., Nuclear Research Center-Negev, P.O.B. 9001, Beer Sheva, Israel
Gordin, S., Volcani Institute for Agricultural Research, Beit Dagan, Israel
Rosenthal, I., Volcani Institute for Agricultural Research, Beit Dagan, Israel
Mutagenic activity in milk and milk products was tested by the Salmonella mammalian-microsome mutagenicity test (Ames test). Salmonella mutants susceptible to base-pair substitution and frameshift mutagens gave positive results with heat-sterilized milk, particularly after activation by the S-9 fraction of microsomes. Maximum increase of His+ revertants was more than twice the spontaneous increase. The chemical specification of the mutagenic activity was not yet defined, but it was present in the chloroform extract of milk. © 1980, American Dairy Science Association. All rights reserved.
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Application of Mutagenicity Test for Milk
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Green, M., Nuclear Research Center-Negev, P.O.B. 9001, Beer Sheva, Israel
Ben-Hur, E., Nuclear Research Center-Negev, P.O.B. 9001, Beer Sheva, Israel
Riklis, E., Nuclear Research Center-Negev, P.O.B. 9001, Beer Sheva, Israel
Gordin, S., Volcani Institute for Agricultural Research, Beit Dagan, Israel
Rosenthal, I., Volcani Institute for Agricultural Research, Beit Dagan, Israel
Application of Mutagenicity Test for Milk
Mutagenic activity in milk and milk products was tested by the Salmonella mammalian-microsome mutagenicity test (Ames test). Salmonella mutants susceptible to base-pair substitution and frameshift mutagens gave positive results with heat-sterilized milk, particularly after activation by the S-9 fraction of microsomes. Maximum increase of His+ revertants was more than twice the spontaneous increase. The chemical specification of the mutagenic activity was not yet defined, but it was present in the chloroform extract of milk. © 1980, American Dairy Science Association. All rights reserved.
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