Co-Authors:
Green, M., Nuclear Research Center-Negev, P.O.B. 9001, Beer Sheva, Israel
Ben-Hur, E., Nuclear Research Center-Negev, P.O.B. 9001, Beer Sheva, Israel
Riklis, E., Nuclear Research Center-Negev, P.O.B. 9001, Beer Sheva, Israel
Gordin, S., Volcani Institute for Agricultural Research, Beit Dagan, Israel
Rosenthal, I., Volcani Institute for Agricultural Research, Beit Dagan, Israel
Abstract:
Mutagenic activity in milk and milk products was tested by the Salmonella mammalian-microsome mutagenicity test (Ames test). Salmonella mutants susceptible to base-pair substitution and frameshift mutagens gave positive results with heat-sterilized milk, particularly after activation by the S-9 fraction of microsomes. Maximum increase of His+ revertants was more than twice the spontaneous increase. The chemical specification of the mutagenic activity was not yet defined, but it was present in the chloroform extract of milk. © 1980, American Dairy Science Association. All rights reserved.
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